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You can go your own way: The targeting signals of trypanosomatid parasites.

作者信息

Pendlebury Max, Lukeš Julius, Hammond Michael J

机构信息

Institute of Parasitology, Biology Centre, Czech Academy of Sciences, and Faculty of Science, University of South Bohemia, České Budějovice (Budweis), Czech Republic.

出版信息

PLoS Pathog. 2025 Aug 1;21(8):e1013326. doi: 10.1371/journal.ppat.1013326. eCollection 2025 Aug.

DOI:10.1371/journal.ppat.1013326
PMID:40748898
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12316301/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/095a/12316301/9ffcfbc07d04/ppat.1013326.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/095a/12316301/139abc8172ef/ppat.1013326.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/095a/12316301/517469bfb4b9/ppat.1013326.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/095a/12316301/9ffcfbc07d04/ppat.1013326.g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/095a/12316301/139abc8172ef/ppat.1013326.g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/095a/12316301/517469bfb4b9/ppat.1013326.g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/095a/12316301/9ffcfbc07d04/ppat.1013326.g003.jpg

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本文引用的文献

1
Distinct structural motifs are necessary for targeting and import of Tim17 in mitochondrion.不同的结构基序对于 Tim17 在 线粒体中的靶向和导入是必需的。
mSphere. 2024 Jan 30;9(1):e0055823. doi: 10.1128/msphere.00558-23. Epub 2024 Jan 9.
2
Trypanosomes as a magnifying glass for cell and molecular biology.锥虫作为细胞和分子生物学的放大镜。
Trends Parasitol. 2023 Nov;39(11):902-912. doi: 10.1016/j.pt.2023.08.004. Epub 2023 Sep 5.
3
Comprehensive sub-mitochondrial protein map of the parasitic protist Trypanosoma brucei defines critical features of organellar biology.
寄生虫原生动物布氏锥虫的综合亚线粒体蛋白质图谱定义了细胞器生物学的关键特征。
Cell Rep. 2023 Sep 26;42(9):113083. doi: 10.1016/j.celrep.2023.113083. Epub 2023 Sep 4.
4
A neo-functionalized homolog of host transmembrane protein controls localization of bacterial endosymbionts in the trypanosomatid Novymonas esmeraldas.真核生物跨膜蛋白的同源物控制细菌内共生体在原生动物绿猴 Novymonas esmeraldas 中的定位。
Curr Biol. 2023 Jul 10;33(13):2690-2701.e5. doi: 10.1016/j.cub.2023.04.060. Epub 2023 May 17.
5
Host-symbiont interactions in Angomonas deanei include the evolution of a host-derived dynamin ring around the endosymbiont division site.在 Angomonas deanei 中，宿主-共生体相互作用包括在共生体分裂部位周围进化出一个由宿主衍生的动力蛋白环。
Curr Biol. 2023 Jan 9;33(1):28-40.e7. doi: 10.1016/j.cub.2022.11.020. Epub 2022 Dec 7.
6
Nucleolar targeting in an early-branching eukaryote suggests a general mechanism for ribosome protein sorting.核仁靶向在一个早期分支的真核生物中表明了核糖体蛋白分拣的一般机制。
J Cell Sci. 2022 Oct 1;135(19). doi: 10.1242/jcs.259701. Epub 2022 Oct 4.
7
Tim17 Updates: A Comprehensive Review of an Ancient Mitochondrial Protein Translocator.Tim17 更新：一种古老的线粒体蛋白转运蛋白的综合综述。
Biomolecules. 2020 Dec 7;10(12):1643. doi: 10.3390/biom10121643.
8
The Functional Characterization of TcMyoF Implicates a Family of Cytostome-Cytopharynx Targeted Myosins as Integral to the Endocytic Machinery of Trypanosoma cruzi.TcMyoF 的功能特征表明，一类细胞口-细胞咽靶向肌球蛋白作为参与克氏锥虫内吞机制的组成部分。
mSphere. 2020 Jun 17;5(3):e00313-20. doi: 10.1128/mSphere.00313-20.
9
Nuclear localization signals in trypanosomal proteins.锥虫蛋白质中的核定位信号
Mol Biochem Parasitol. 2019 Apr;229:15-23. doi: 10.1016/j.molbiopara.2019.02.003. Epub 2019 Feb 14.
10
Biogenesis of a Mitochondrial Outer Membrane Protein in : TARGETING SIGNAL AND DEPENDENCE ON A UNIQUE BIOGENESIS FACTOR.线粒体外膜蛋白在中的生物合成：靶向信号及对一种独特生物合成因子的依赖性
J Biol Chem. 2017 Feb 24;292(8):3400-3410. doi: 10.1074/jbc.M116.755983. Epub 2017 Jan 18.