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密尔沃基县贫民农场公墓中布鲁氏菌病感染的证据。

Evidence of brucellosis infection in the Milwaukee County Poor Farm Cemetery.

作者信息

Werner Helen

机构信息

Biology, Beloit College, Beloit, Wisconsin, United States.

出版信息

MicroPubl Biol. 2025 Jul 18;2025. doi: 10.17912/micropub.biology.001601. eCollection 2025.

Abstract

Forty-seven skeletonized individuals from the Milwaukee County Poor Farm Cemetery (MCPFC) had DNA extracted from their dental calculus to look for the presence of respiratory pathogens. The MCPFC is curated by the Archaeology Laboratory at the University of Wisconsin-Milwaukee. According to the death records, respiratory infections and pneumonias were a leading cause of death. Polymerase Chain Reaction was run to examine the extracted DNA for evidence of , species, and . Three individuals had IS711 present in their dental calculus, suggesting infection by species. This is the first documented brucellosis DNA successfully extracted from dental calculus.

摘要

从密尔沃基县贫民农场公墓(MCPFC)的47具骨骼标本中提取了牙结石中的DNA,以寻找呼吸道病原体的存在。MCPFC由威斯康星大学密尔沃基分校的考古实验室管理。根据死亡记录,呼吸道感染和肺炎是主要死因。进行聚合酶链反应以检测提取的DNA中是否存在[此处原文缺失部分物种名称]物种和[此处原文缺失部分物种名称]。三名个体的牙结石中存在IS711,表明感染了[此处原文缺失部分物种名称]物种。这是首次成功从牙结石中提取出布鲁氏菌病DNA的记录。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9a44/12317341/eb7a1ce6fa80/25789430-2025-micropub.biology.001601.jpg

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