Madsen F, Secher N H, Kay L, Kok-Jensen A, Rube N
Eur J Respir Dis. 1985 Sep;67(3):167-76.
The effect of inspiratory muscle training (IMT) three times daily for 6 weeks was compared with that of general physical training (PT) (stair climbing) in 10 out-patients with severe chronic obstructive pulmonary disease (COPD). PT improved 12 min walking distance (12MWD) by 19% (1-28), stair climbing ability (SCA) over four floors at maximum speed by 11% (3-50), maximum oxygen uptake by 10% (2-33), inspiratory flow by 85% (19-113) and improved an index of breathlessness by 44% (3-786). During IMT, 12MWD and SCA decreased by 8% (0-33) and 10% (0-161), respectively, and the other variables decreased by 6-10%. No changes were seen in ventilation during maximum exercise, in maximum inspiratory and expiratory pressures, or in variables measured during spirometry. Thus work capacity can be improved by training in COPD maybe because of an increase in inspiratory flow rate, but without a change in maximum exercise ventilation.
对10名重度慢性阻塞性肺疾病（COPD）门诊患者进行研究，比较每日3次、为期6周的吸气肌训练（IMT）与一般体育训练（PT，爬楼梯）的效果。PT使12分钟步行距离（12MWD）提高了19%（1%-28%），以最快速度爬四层楼梯的能力（SCA）提高了11%（3%-50%），最大摄氧量提高了10%（2%-33%），吸气流量提高了85%（19%-113%），并使呼吸困难指数改善了44%（3%-786%）。在IMT期间，12MWD和SCA分别下降了8%（0%-33%）和10%（0%-161%），其他变量下降了6%-10%。最大运动时的通气量、最大吸气和呼气压力或肺活量测定期间测量的变量均无变化。因此，COPD患者的工作能力可通过训练得到改善，这可能是由于吸气流速增加，但最大运动通气量无变化。
