Vargas M, Puig A, de la Maza M, Morales P, Vargas D, Bunout B, Gattás V, Hirsch S
Instituto Nacional de Enfermedades Respiratorias y Cirugía Torácica (INERyCT), Universidad de Chile, Santiago.
Rev Med Chil. 1995 Oct;123(10):1225-34.
To assess prospectively the effects of a controlled program of inspiratory muscle training program and nutritional support in patients with chronic obstructive lung disease (COPD).
Twenty-three patients with COPD were randomly assigned into four groups. Group I received a 1000 kcal/day nutritional supplement, given as a casein based enteral nutritional formula; group III was subjected to inspiratory muscle training, using an inexpensive pressure threshold load valve constructed according to the Appropriate Technology principles of the WHO, adjusted at 30% of Maximal Inspiratory Mouth Pressure and received also the nutritional supplement; group IV was trained but did not receive the nutritional supplement and group II was not trained nor supplemented. Patients were studied during three months and monthly, inspiratory muscle function, exercise capacity and anthropometry were measured.
A significant improvement in exercise capacity, maximal inspiratory pressure and inspiratory muscle endurance was observed in the four groups throughout the study. Trained subjects had greater improvement in their inspiratory muscle endurance, compared to untrained subjects. Nutritional support had no effect in inspiratory muscle function or exercise capacity. No changes in anthropometric measures were observed.
The pressure threshold load valve used in this study, improved inspiratory muscle endurance and nutritional support had no effect in patients with COPD.
前瞻性评估控制性吸气肌训练计划和营养支持对慢性阻塞性肺疾病(COPD)患者的影响。
23例COPD患者被随机分为四组。第一组接受基于酪蛋白的肠内营养配方,每日补充1000千卡热量;第三组采用根据世界卫生组织适宜技术原则制作的廉价压力阈值负荷阀进行吸气肌训练,将其调整至最大吸气压的30%,同时也接受营养补充;第四组接受训练但未接受营养补充,第二组既未接受训练也未接受补充。对患者进行为期三个月的研究,每月测量吸气肌功能、运动能力和人体测量指标。
在整个研究过程中,四组患者的运动能力、最大吸气压和吸气肌耐力均有显著改善。与未训练的患者相比,训练过的患者吸气肌耐力改善更大。营养支持对吸气肌功能或运动能力没有影响。人体测量指标未见变化。
本研究中使用的压力阈值负荷阀改善了吸气肌耐力,营养支持对COPD患者没有影响。