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X射线暗场成像与小角X射线散射测量之间的关系。

How X-ray dark-field imaging relates to small-angle X-ray scattering measurements.

作者信息

Magnin Clara, Fernández Martínez Manuel, Mihai Cenda Dan, Lantz Blandine, Barton Scott, Faure Bertrand, Brun Emmanuel

机构信息

Univ. Grenoble Alpes, Inserm UA7, Strobe, Grenoble, France.

Xenocs SAS, Grenoble, France.

出版信息

J Appl Crystallogr. 2025 Jun 20;58(Pt 4):1347-1354. doi: 10.1107/S1600576725004017. eCollection 2025 Aug 1.

DOI:10.1107/S1600576725004017
PMID:40765975
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12321030/
Abstract

Dark-field (DF) imaging is a recent X-ray imaging modality which is promising because it gives access to information not resolved in conventional transmission X-ray imaging. The DF technique was first introduced as a loss of visibility of the grating interferometry modulations. DF signal is now measured with all the different X-ray phase contrast setups such as beam tracking or modulation-based imaging. Using a dedicated setup [Magnin (2023). , 5839-5842], we present in the present article combined measurements of small-angle X-ray scattering and DF signal on the same material. We confirm that DF imaging is sensitive to multiple refraction from a sample, as can be found in the literature on lung imaging, but we show that the DF signal is also sensitive to scattering events. Finally, we measure a porous membrane that creates both types of signal (scattering and refraction), showing that, contrary to existing models, it is difficult to be quantitative about DF.

摘要

暗场(DF)成像作为一种新型的X射线成像方式,因其能够获取传统透射X射线成像中无法分辨的信息而备受关注。DF技术最初是作为光栅干涉调制可见度的损失而引入的。目前,在所有不同的X射线相衬成像设置中,如光束跟踪或基于调制的成像中,都可以测量DF信号。通过使用一种专门的设置[Magnin(2023),5839 - 5842],我们在本文中展示了在同一种材料上同时进行小角X射线散射和DF信号的测量。我们证实,正如在肺部成像文献中所发现的那样,DF成像对样品的多次折射敏感,但我们也表明DF信号对散射事件同样敏感。最后,我们测量了一种能同时产生两种信号(散射和折射)的多孔膜,这表明,与现有模型相反,很难对DF进行定量分析。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d83/12321030/380aaa148953/j-58-01347-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d83/12321030/dfbb69e3acab/j-58-01347-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d83/12321030/baff27e533a1/j-58-01347-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d83/12321030/da8bc902a3ea/j-58-01347-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d83/12321030/1d1cb4cea171/j-58-01347-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d83/12321030/380aaa148953/j-58-01347-fig5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d83/12321030/dfbb69e3acab/j-58-01347-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d83/12321030/baff27e533a1/j-58-01347-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d83/12321030/da8bc902a3ea/j-58-01347-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d83/12321030/1d1cb4cea171/j-58-01347-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3d83/12321030/380aaa148953/j-58-01347-fig5.jpg

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本文引用的文献

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Laboratory-based x-ray dark-field microscopy.基于实验室的X射线暗场显微镜术。
Phys Rev Appl. 2023 Dec;20(6). doi: 10.1103/physrevapplied.20.064039. Epub 2023 Dec 21.
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Dark-field and directional dark-field on low-coherence x ray sources with random mask modulations: validation with SAXS anisotropy measurements.基于随机掩膜调制的低相干X射线源的暗场和定向暗场成像:小角X射线散射各向异性测量验证
Opt Lett. 2023 Nov 15;48(22):5839-5842. doi: 10.1364/OL.501716.
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Directional dark-field retrieval with single-grid x-ray imaging.基于单光栅 X 射线成像的暗场方向重建。
Opt Express. 2023 Mar 27;31(7):11578-11597. doi: 10.1364/OE.480031.
4
Quantifying the x-ray dark-field signal in single-grid imaging.单网格成像中X射线暗场信号的量化
Opt Express. 2022 Mar 28;30(7):10899-10918. doi: 10.1364/OE.451834.
5
Qualitative and Quantitative Assessment of Emphysema Using Dark-Field Chest Radiography.使用暗场胸部 X 线摄影术对肺气肿进行定性和定量评估。
Radiology. 2022 Apr;303(1):119-127. doi: 10.1148/radiol.212025. Epub 2022 Jan 11.
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X-ray dark-field chest imaging for detection and quantification of emphysema in patients with chronic obstructive pulmonary disease: a diagnostic accuracy study.X 射线暗场胸部成像在慢性阻塞性肺疾病患者肺气肿检测和定量中的诊断准确性研究。
Lancet Digit Health. 2021 Nov;3(11):e733-e744. doi: 10.1016/S2589-7500(21)00146-1.
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X-ray Dark-Field Chest Imaging: Qualitative and Quantitative Results in Healthy Humans.X 射线暗场胸部成像:健康人体的定性和定量结果。
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X-ray dark-field tomography reveals tooth cracks.X 射线暗场层析成像显示牙齿裂纹。
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Comparison of X-ray speckle-based imaging deflection retrieval algorithms for the optimization of radiation dose.基于 X 射线散斑的成像偏折检索算法比较,用于优化辐射剂量。
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X-ray dark-field imaging of the human lung-A feasibility study on a deceased body.人体肺部的 X 射线暗场成像——尸体上的一项可行性研究。
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