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不同剂量皮质类固醇超声引导下肩峰下滑囊注射治疗肩峰下滑囊炎的疗效:一项回顾性研究

Effect of Ultrasound-Guided Subacromial Bursa Injections With Various Doses of Corticosteroid in Subacromial Bursitis: A Retrospective Study.

作者信息

Yatish R, B K Ashok Kumar, Suvarna Abhinav A, Channappa T S, Jayaram Manju, Shivakumar H B

机构信息

Orthopedics, Kempegowda Institute of Medical Sciences and Research Center, Bangalore, IND.

Pain Management, Kempegowda Institute of Medical Sciences and Research Center, Bangalore, IND.

出版信息

Cureus. 2025 Aug 3;17(8):e89307. doi: 10.7759/cureus.89307. eCollection 2025 Aug.

DOI:10.7759/cureus.89307
PMID:40766090
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12322512/
Abstract

BACKGROUND

Subacromial bursitis is a common cause of shoulder pain and functional limitation, due to inflammation of the subacromial bursa. Corticosteroid injections are widely used in cases unresponsive to conservative treatments. However, the optimal dose for achieving sustained symptom relief with minimal adverse effects, especially when administered under ultrasound guidance, remains a topic of clinical interest. This study evaluates the efficacy of different corticosteroid doses delivered via ultrasound-guided subacromial bursa injection.

METHODOLOGY

This retrospective study was conducted at a tertiary care center between May 2018 and June 2023. Patients aged 30-60 years with MRI-confirmed subacromial bursitis who failed conservative treatment for at least three months were included. Subjects were divided into two groups: a low-dose group receiving 10 mg triamcinolone with 1% lignocaine and a high-dose group receiving 20 mg triamcinolone with 1% lignocaine. Injections were administered under ultrasound guidance using a linear probe. Pain was assessed using the Numerical Rating Scale (NRS) at baseline, and at one week, one month, three months, and six months post-intervention. Data were analyzed using t-tests and chi-square tests.

RESULTS

Both groups showed significant reductions in pain scores at all post-injection time points ( < 0.05). The high-dose group demonstrated more substantial and sustained improvement in pain relief, with mean NRS scores decreasing from 8.1 at baseline to 2.4 at six months, compared to a decline from 7.9 to 3.5 in the low-dose group. Adverse events were minimal and similar across both groups.

CONCLUSIONS

Ultrasound-guided corticosteroid injections represent a safe and effective treatment for subacromial bursitis, with higher doses of triamcinolone offering longer-lasting pain relief. The technique improves precision and minimizes risk, making it a valuable tool in managing refractory shoulder pain. Further prospective studies are recommended to validate these findings and develop standardized dosing protocols.

摘要

背景

肩峰下滑囊炎是肩部疼痛和功能受限的常见原因,是由肩峰下滑囊炎症引起的。皮质类固醇注射广泛应用于对保守治疗无反应的病例。然而,以最小的不良反应实现持续症状缓解的最佳剂量,尤其是在超声引导下给药时,仍然是临床关注的话题。本研究评估了通过超声引导肩峰下滑囊注射给予不同皮质类固醇剂量的疗效。

方法

本回顾性研究于2018年5月至2023年6月在一家三级医疗中心进行。纳入年龄在30至60岁之间、MRI确诊为肩峰下滑囊炎且保守治疗失败至少三个月的患者。受试者分为两组:低剂量组接受10毫克曲安奈德加1%利多卡因,高剂量组接受20毫克曲安奈德加1%利多卡因。使用线性探头在超声引导下进行注射。在基线时以及干预后1周、1个月、3个月和6个月使用数字评分量表(NRS)评估疼痛。使用t检验和卡方检验分析数据。

结果

两组在所有注射后时间点的疼痛评分均显著降低(<0.05)。高剂量组在疼痛缓解方面表现出更显著和持续的改善,平均NRS评分从基线时的8.1降至6个月时的2.4,而低剂量组从7.9降至3.5。两组的不良事件均极少且相似。

结论

超声引导下皮质类固醇注射是肩峰下滑囊炎的一种安全有效的治疗方法,较高剂量的曲安奈德可提供更持久的疼痛缓解。该技术提高了精准度并将风险降至最低,使其成为治疗难治性肩部疼痛的宝贵工具。建议进一步进行前瞻性研究以验证这些发现并制定标准化给药方案。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12b9/12322512/f4fe65e3e9f1/cureus-0017-00000089307-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12b9/12322512/3dccf4224de5/cureus-0017-00000089307-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12b9/12322512/f4fe65e3e9f1/cureus-0017-00000089307-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12b9/12322512/3dccf4224de5/cureus-0017-00000089307-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/12b9/12322512/f4fe65e3e9f1/cureus-0017-00000089307-i02.jpg

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本文引用的文献

1
A systematic review of the global prevalence and incidence of shoulder pain.一项全球肩痛患病率和发病率的系统评价。
BMC Musculoskelet Disord. 2022 Dec 8;23(1):1073. doi: 10.1186/s12891-022-05973-8.
2
Ultrasound-guided bursal injections.超声引导下的滑囊注射。
Skeletal Radiol. 2023 May;52(5):967-978. doi: 10.1007/s00256-022-04153-y. Epub 2022 Aug 26.
3
Systematic review and meta-analysis on the effectiveness of ultrasound-guided versus landmark corticosteroid injection in the treatment of shoulder pain: an update.
超声引导与解剖标志定位皮质类固醇注射治疗肩部疼痛的有效性的系统评价和荟萃分析:更新。
J Ultrasound. 2023 Sep;26(3):593-604. doi: 10.1007/s40477-022-00684-1. Epub 2022 May 6.
4
Subacromial Bursa: A Neglected Tissue Is Gaining More and More Attention in Clinical and Experimental Research.肩峰下囊:一个在临床和实验研究中越来越受到关注的被忽视组织。
Cells. 2022 Feb 14;11(4):663. doi: 10.3390/cells11040663.
5
Histological and molecular features of the subacromial bursa of rotator cuff tears compared to non-tendon defects: a pilot study.肩袖撕裂的肩峰下滑囊组织学和分子特征与非肌腱缺损的比较:一项初步研究。
BMC Musculoskelet Disord. 2021 Oct 14;22(1):877. doi: 10.1186/s12891-021-04752-1.
6
Ultrasound-guided versus blind subacromial corticosteroid and local anesthetic injection in the treatment of subacromial impingement syndrome: A randomized study of efficacy.超声引导与盲法肩峰下皮质类固醇和局部麻醉剂注射治疗肩峰下撞击综合征:一项疗效的随机研究。
Jt Dis Relat Surg. 2020;31(1):115-22. doi: 10.5606/ehc.2020.71056.
7
Ultrasound-guided subacromial-subdeltoid bursa corticosteroid injections: a study of short- and long-term outcomes.超声引导肩峰下-三角肌下囊皮质类固醇注射:短期和长期疗效研究。
Clin Radiol. 2018 Aug;73(8):760.e7-760.e12. doi: 10.1016/j.crad.2018.03.016. Epub 2018 Jun 18.
8
Comparative outcomes of combined corticosteroid with low volume compared to high volume of local anesthetic in subacromial injection for impingement syndrome: systematic review and meta-analysis of RCTs.肩峰下注射皮质类固醇联合小剂量与大剂量局部麻醉药治疗撞击综合征的比较结果:随机对照试验的系统评价和荟萃分析
Eur J Orthop Surg Traumatol. 2018 Apr;28(3):397-407. doi: 10.1007/s00590-017-2056-z. Epub 2017 Oct 12.
9
Prevalence of abnormalities on shoulder MRI in symptomatic and asymptomatic older adults.有症状和无症状的老年人肩部MRI异常的患病率。
Int J Rheum Dis. 2014 Nov;17(8):863-71. doi: 10.1111/1756-185X.12476. Epub 2014 Oct 8.
10
Subacromial impingement syndrome: effectiveness of pharmaceutical interventions-nonsteroidal anti-inflammatory drugs, corticosteroid, or other injections: a systematic review.肩峰下撞击综合征:药物干预(非甾体抗炎药、皮质类固醇或其他注射剂)的疗效:系统评价。
Arch Phys Med Rehabil. 2013 May;94(5):961-76. doi: 10.1016/j.apmr.2012.11.041. Epub 2012 Dec 12.