衰弱在实体器官移植患者评估中的临床应用
Clinical Application of Frailty in the Evaluation of Solid Organ Transplant Patients.
作者信息
Cimeno Arielle, Madariaga Maria Lucia L, Basu Arpita, Pezzuto Dani, Parsons Ronald, Huisingh-Scheetz Megan
机构信息
Department of Surgery, University of Chicago, Chicago, IL, USA.
Department of Medicine, Emory University, Atlanta, GA, USA.
出版信息
Curr Transplant Rep. 2024 Jun;11(2):110-119. doi: 10.1007/s40472-024-00436-6. Epub 2024 Apr 23.
PURPOSE OF REVIEW
Frailty is increasingly recognized as an important predictor of mortality and morbidity in patients across various medical subspecialties. The purpose of this review is to assess how frailty and markers of functional status are viewed within the field of transplant and incorporated into patient evaluations.
RECENT FINDINGS
Frailty has been shown to influence patient and graft outcomes and many centers incorporate some form of frailty assessment during transplant candidacy evaluation. However, the optimal methods for assessing frailty have not been defined for solid organ transplant populations, and there is no standard approach among different centers. Subjective measures of functional status are recorded in national registries at the time of waitlisting but are largely not used when determining waitlist priority.
SUMMARY
This review focuses on currently used tools for assessing frailty in transplant patients and consensus recommendations for future application of frailty in this population.
综述目的
衰弱日益被视为各医学亚专业患者死亡率和发病率的重要预测指标。本综述的目的是评估在移植领域中衰弱及功能状态标志物是如何被看待的，以及如何纳入患者评估中。
最新发现
衰弱已被证明会影响患者和移植物的预后，许多中心在移植候选资格评估期间采用某种形式的衰弱评估。然而，对于实体器官移植人群，尚未确定评估衰弱的最佳方法，不同中心也没有标准方法。在列入等待名单时，国家登记处记录了功能状态的主观指标，但在确定等待名单优先级时基本未被使用。
总结
本综述重点关注目前用于评估移植患者衰弱的工具，以及关于未来在该人群中应用衰弱评估的共识性建议。
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