James Sydney H, Galvan Thania, Zollicoffer Ashley, Strauss Gregory P
Department of Psychology, University of Georgia, 125 Baldwin St, Athens, GA, 30602, USA.
Department of Psychology, Louisiana State University, Baton Rouge, LA, USA.
Soc Psychiatry Psychiatr Epidemiol. 2025 Aug 6. doi: 10.1007/s00127-025-02980-7.
Although current interventions have proven effective for improving outcomes for individuals with psychotic disorders, this population continues to encounter challenges and health disparities. Recently, researchers have investigated how social determinants of health influence the incidence and outcomes of psychotic disorders. In particular, neighborhood deprivation (i.e., a composite index capturing the social, material, and environmental challenges of a particular area relative to the broader area [1]), has been investigated in numerous studies on psychotic disorders but research has yet to consolidate and quantify its significance. The current meta-analysis assesses neighborhood deprivation and its relationship to psychotic disorder incidence and symptoms.
Articles published prior to April 1, 2024 were identified via two bibliographic databases: PubMed and PsycINFO. The literature search yielded 17 studies consisting of 59,719 cases for the meta-analysis investigating the relation between neighborhood deprivation and psychotic disorder incidence. Six studies of 2,790 cases were included in the meta-analysis assessing the relation between neighborhood deprivation and psychotic disorder symptoms.
There was a robust relation between psychotic disorder incidence and neighborhood deprivation, such that as neighborhood deprivation within an area increased so too did the incidence. There was no evidence of a substantial relationship between neighborhood deprivation and psychotic disorder symptoms.
The results of this study identified a social determinant of health that has high relevance to the incidence of psychotic disorders. Findings underscore the need to develop multi-level interventions to address neighborhood deprivation and reduce resource inequalities across geographical locations.
尽管目前的干预措施已被证明对改善精神障碍患者的预后有效，但这一人群仍面临挑战和健康差距。最近，研究人员调查了健康的社会决定因素如何影响精神障碍的发病率和预后。特别是，邻里贫困（即一个综合指数，反映特定区域相对于更广泛区域的社会、物质和环境挑战[1]）在众多关于精神障碍的研究中得到了调查，但研究尚未整合并量化其重要性。当前的荟萃分析评估了邻里贫困及其与精神障碍发病率和症状的关系。
通过两个文献数据库：PubMed和PsycINFO，识别出2024年4月1日前发表的文章。文献检索产生了17项研究，共59719例，用于荟萃分析邻里贫困与精神障碍发病率之间的关系。六项研究共2790例被纳入荟萃分析，以评估邻里贫困与精神障碍症状之间的关系。
精神障碍发病率与邻里贫困之间存在密切关系，即随着一个地区邻里贫困程度的增加，发病率也会增加。没有证据表明邻里贫困与精神障碍症状之间存在实质性关系。
本研究结果确定了一个与精神障碍发病率高度相关的健康社会决定因素。研究结果强调需要制定多层次干预措施，以解决邻里贫困问题，并减少不同地理位置之间的资源不平等。
