Camargo Juliana Dantas de Araújo Santos, Camargo Sávio F, de Souza Amaxsell Thiago Barros, Freitas Ana Karla M S de Oliveira, Nobre Maria L, Sarmento Ayane C A, de Aquino Antônio C Q, Oliveira Ana Beatriz D, Serquiz Nicoli, Gonçalves Ana Katherine
Postgraduate Program in Health Sciences, Federal University of Rio Grande do Norte (UFRN), Natal, Brazil.
Postgraduate Program in Sciences Applied to Women's Health, Federal University of Rio Grande do Norte (UFRN), Natal, Brazil.
J Educ Health Promot. 2025 Jul 4;14:264. doi: 10.4103/jehp.jehp_1813_24. eCollection 2025.
Breast cancer is responsible for the highest rates of incidence and mortality among neoplasms in women. There is a lack of evidence regarding the different domains and intensities of physical activity (PA) in relation to the risk of breast cancer occurrence in menopause. The objective will be to evaluate the impact of different domains and intensities of PA in preventing breast cancer in postmenopausal women. Databases, including MEDLINE/PubMed, Scopus, Web of Science, and Embase, will be used for the search. A search strategy was developed to retrieve observational studies (case-control and cohort) that have evaluated occurrence of breast cancer and practice of PA in postmenopausal women. No date or language restrictions will be applied. Two authors will independently select the studies meeting the inclusion criteria by screening the title, abstract, and full text. Data will be extracted, and the risk of bias will be evaluated using the Newcastle-Ottawa scale (NOS). Review Manager 5.4.1 and software R version 4.3.1 will be used for data synthesis. The Grading of Recommendation Assessment, Development, and Evaluation will be used to assess the strength of the evidence. This systematic review and meta-analysis will summarize the comparative efficacy of types, domains and intensities of PA in reducing the risk of breast cancer in postmenopausal women.
乳腺癌是女性肿瘤中发病率和死亡率最高的疾病。关于绝经后身体活动（PA）的不同领域和强度与乳腺癌发生风险之间的关系，目前缺乏证据。本研究的目的是评估不同领域和强度的PA对绝经后女性预防乳腺癌的影响。将使用包括MEDLINE/PubMed、Scopus、Web of Science和Embase在内的数据库进行检索。制定了检索策略，以检索评估绝经后女性乳腺癌发生情况和PA实践的观察性研究（病例对照研究和队列研究）。不设日期或语言限制。两名作者将通过筛选标题、摘要和全文，独立选择符合纳入标准的研究。将提取数据，并使用纽卡斯尔-渥太华量表（NOS）评估偏倚风险。将使用Review Manager 5.4.1和软件R版本4.3.1进行数据合成。将使用推荐评估、制定和评价分级系统来评估证据的强度。本系统评价和荟萃分析将总结PA的类型、领域和强度在降低绝经后女性乳腺癌风险方面的比较疗效。
