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睡眠与冠心病之间的关联:综述

The Correlation Between Sleep and Coronary Heart Disease: A Review.

作者信息

Shi Qingbo, Gao Yang, Shi Zhuocheng, Li Muwei

机构信息

Department of Cardiology, Central China Fuwai Hospital of Zhengzhou University, Fuwai Central China Cardiovascular Hospital, 450000 Zhengzhou, Henan, China.

Department of Cardiology, Zhengzhou University People's Hospital, Henan Provincial People's Hospital, 450000 Zhengzhou, Henan, China.

出版信息

Rev Cardiovasc Med. 2025 Jul 18;26(7):37252. doi: 10.31083/RCM37252. eCollection 2025 Jul.


DOI:10.31083/RCM37252
PMID:40776943
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12326418/
Abstract

Coronary heart disease (CHD), which is characterized by the coronary arteries narrowing or becoming obstructed due to atherosclerosis, leads to myocardial ischemia, hypoxia, or necrosis. Owing to an aging population and lifestyle changes, the incidence of CHD and subsequent mortality rates continue to rise, making CHD one of the leading causes of disability and death worldwide. Hypertension, diabetes, hyperlipidemia, smoking, obesity, and genetic factors are considered major risk factors for CHD; however, these factors do not fully explain the complexity and diversity in the etiology of CHD. Sleep, an indispensable part of human physiological processes, is crucial for maintaining physical and mental health. In recent years, the rapid pace of modern life has led to an increasing number of patients experiencing an insufficient amount of sleep, declining sleep quality, and sleep disorders. Therefore, the correlation between sleep and CHD has become a focal point in current research. This review aims to address the relationship between sleep duration, quality, and sleep disorder-related diseases with CHD and emphasizes potential underlying mechanisms and possible clinical implications. Moreover, this review aimed to provide a theoretical basis and clinical guidance for the prevention and treatment of CHD.

摘要

冠心病(CHD)的特征是冠状动脉因动脉粥样硬化而变窄或阻塞,导致心肌缺血、缺氧或坏死。由于人口老龄化和生活方式的改变,冠心病的发病率和随后的死亡率持续上升,使冠心病成为全球致残和死亡的主要原因之一。高血压、糖尿病、高脂血症、吸烟、肥胖和遗传因素被认为是冠心病的主要危险因素;然而,这些因素并不能完全解释冠心病病因的复杂性和多样性。睡眠是人类生理过程中不可或缺的一部分,对维持身心健康至关重要。近年来,现代生活的快节奏导致越来越多的患者睡眠不足、睡眠质量下降和睡眠障碍。因此,睡眠与冠心病之间的相关性已成为当前研究的焦点。本综述旨在探讨睡眠时间、质量以及与睡眠障碍相关疾病与冠心病之间的关系,并强调潜在的潜在机制和可能的临床意义。此外,本综述旨在为冠心病的预防和治疗提供理论依据和临床指导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1795/12326418/1398d1bc553d/2153-8174-26-7-37252-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1795/12326418/1398d1bc553d/2153-8174-26-7-37252-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1795/12326418/1398d1bc553d/2153-8174-26-7-37252-g1.jpg

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本文引用的文献

[1]
Gender correlation between sleep duration and risk of coronary heart disease: a systematic review and meta-analysis.

Front Cardiovasc Med. 2025-3-25

[2]
Impact of Obstructive Sleep Apnea on Cardiovascular Health: A Systematic Review.

Cureus. 2024-10-20

[3]
Inflammation in atherosclerosis: pathophysiology and mechanisms.

Cell Death Dis. 2024-11-11

[4]
The Effects of Continuous Positive Airway Pressure Therapy for Secondary Cardiovascular Prevention in Patients with Obstructive Sleep Apnoea: A Systematic Review and Meta-Analysis.

Rev Cardiovasc Med. 2022-5-27

[5]
Impact of Obstructive Sleep Apnea and Sympathetic Nervous System on Cardiac Health: A Comprehensive Review.

J Cardiovasc Dev Dis. 2024-6-30

[6]
The Effect of Sleep Quality on Coronary Lesion Severity and Prognosis in the Young Acute Coronary Syndrome Population.

J Cardiovasc Dev Dis. 2024-2-19

[7]
Sleep patterns and risks of incident cardiovascular disease and mortality among people with type 2 diabetes: a prospective study of the UK Biobank.

Diabetol Metab Syndr. 2024-1-11

[8]
Triglyceride-glucose index and obstructive sleep apnea: a systematic review and meta-analysis.

Lipids Health Dis. 2024-1-8

[9]
Obstructive Sleep Apnoea (OSA) and early atherosclerosis: The role of microbiota and EVs.

Pulmonology. 2024

[10]
The European Insomnia Guideline: An update on the diagnosis and treatment of insomnia 2023.

J Sleep Res. 2023-12

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