Hertz Julian T, Sakita Francis M, Munshi Zaheer Rik, Rahim Faraan O, Mganga Daniel, Kachenje Arafa, Munisi James J, Pyne Abigail S, Bashaka Prosper, Kilungu Adamu, Aboud Ayshat Mussa, Bosworth Hayden B, Bettger Janet Prvu
Department of Emergency Medicine, Duke University, Durham, North Carolina, USA.
Duke Global Health Institute, Durham, North Carolina, USA.
Ann Glob Health. 2025 Aug 5;91(1):43. doi: 10.5334/aogh.4651. eCollection 2025.
Uptake of evidence-based care for acute myocardial infarction (AMI) is limited in Tanzania. To address this, a tailored intervention, the Multicomponent Intervention to Improve Acute Myocardial Infarction Care (MIMIC), was co-designed by an interdisciplinary team. To determine implementation outcomes from a pilot trial of the MIMIC intervention in a Tanzanian emergency department (ED). The MIMIC intervention was implemented by the ED staff for one year. Fidelity, penetration, and costs were observed for each of the intervention components: designated champions to audit care, an online training module for staff, a triage card for nurses to flag patients with AMI symptoms, pocket cards summarizing AMI management for physicians, and an educational pamphlet for patients. Thirty days following enrollment, patient participants were contacted via telephone to inquire whether they had read the pamphlet. Physician champions and nurse champions were actively engaged in the intervention across the twelve-month study period. Fidelity to the pocket card was excellent, with all 22 (100%) physicians observed to have ever brought their pocket cards to work, and penetration across physician-shifts was 96.1% (1835/1910). The training module was started by 20 out of the 22 (91%) physicians and 25 of the 32 (78%) nurses observed. Penetration, measured by module completion, was the same for physicians (20 of 22, 91%) but lower among nurses (21 of 32, 65.6%). Triage cards were used for 453 out of the 577 (78.5%) patients with chest pain or dyspnea. Fidelity to patients with AMI receiving the educational pamphlet was 37.6% (53 of 141). Only 22 of the 39 (56%) surviving AMI patients who received the pamphlet reported reading it, with most of the rest reporting being unaware that they had received it. The total annual cost of the MIMIC intervention was USD 1324.24. There was high variability in fidelity and penetration of the individual intervention components. Future studies should explore reasons for incomplete penetration and analyze cost-effectiveness for scale-up efforts across Tanzania.
在坦桑尼亚,急性心肌梗死(AMI)基于证据的护理的采用情况有限。为解决这一问题,一个跨学科团队共同设计了一种针对性干预措施,即改善急性心肌梗死护理多组分干预措施(MIMIC)。目的是确定在坦桑尼亚一家急诊科(ED)对MIMIC干预进行试点试验的实施结果。MIMIC干预由急诊科工作人员实施了一年。对每个干预组分的保真度、渗透率和成本进行了观察:指定负责人审核护理情况、为工作人员提供在线培训模块、为护士提供用于标记有AMI症状患者的分诊卡、为医生总结AMI管理的袖珍卡片以及为患者提供的教育手册。入组30天后,通过电话联系患者参与者询问他们是否阅读了手册。医生负责人和护士负责人在为期十二个月的研究期间积极参与了干预。袖珍卡片的保真度极佳,观察到所有22名(100%)医生都曾带着袖珍卡片上班,医生轮班期间的渗透率为96.1%(1835/1910)。观察到22名医生中的20名(91%)和32名护士中的25名(78%)开始使用培训模块。以模块完成情况衡量的渗透率,医生相同(22名中的20名,91%),但护士中较低(32名中的21名,65.6%)。577名胸痛或呼吸困难患者中有453名(78.5%)使用了分诊卡。接受教育手册的AMI患者的保真度为37.6%(141名中的53名)。在收到手册的39名(56%)存活AMI患者中,只有22名报告阅读了手册,其余大多数报告称不知道自己收到了手册。MIMIC干预的年度总成本为1324.24美元。各个干预组分的保真度和渗透率存在很大差异。未来的研究应探讨渗透率不完全的原因,并分析在坦桑尼亚扩大规模努力的成本效益。