Squires Oliver
Paediatrics, Perth Children's Hospital, Perth, AUS.
Cureus. 2025 Jul 10;17(7):e87688. doi: 10.7759/cureus.87688. eCollection 2025 Jul.
The objective of this bibliometric analysis was to evaluate trends in paediatric epilepsy treatment research from 2005 to 2025. Through assessing which journals, countries, authors, and institutions have been the most productive and mapping trends in keywords used over time, the study aims to reveal emerging areas of interest and inspire ideas for future research. A total of 1418 relevant documents were retrieved from the Web of Science database. Documents outside of the target time period and non-English documents were excluded. From the 1152 remaining documents, 17 duplicates were removed using OpenRefine (OpenRefine). The final 1135 documents were then analysed using VosViewer (VOSviewer - Visualizing scientific landscapes) and Bibliometrix (https://www.bibliometrix.org/). The analysis revealed a stable number of annual global publications until a notable increase since 2018. The USA leads the way with the greatest research output (298 articles) and the highest number of total citations (6565). Harvard University emerged as the most productive institution (111 articles), whilst Epilepsia was the most productive journal (253 articles). Keyword co-occurrence analysis revealed a shift in research from earlier documents focusing more on traditional drug therapies to more recent articles focusing on cannabidiol based therapies, laser ablation, and vagal nerve stimulation. This bibliometric analysis provides new insights into the evolution of paediatric epilepsy treatment research. It helps to demonstrate the leading contributors in the field over the last 20 years, as well as highlighting emerging new trends. The results of the analysis underline the shift in the research away from more traditional treatments to investigating alternative therapies, including cannabidiol based therapies, dietary interventions, laser ablation, and vagal nerve stimulation. Through identifying these trends in the research and mapping author collaboration networks, it is hoped that this study can provide a foundational reference for researchers when planning future studies.
这项文献计量分析的目的是评估2005年至2025年小儿癫痫治疗研究的趋势。通过评估哪些期刊、国家、作者和机构的产出最多，并绘制随时间推移使用的关键词趋势图，该研究旨在揭示新出现的感兴趣领域，并激发未来研究的思路。从科学网数据库中检索到1418篇相关文献。排除目标时间段之外的文献和非英文文献。从剩余的1152篇文献中，使用OpenRefine（一款数据清理软件）去除了17篇重复文献。然后使用VosViewer（一款科学知识图谱可视化软件）和Bibliometrix（https://www.bibliometrix.org/）对最终的1135篇文献进行分析。分析显示，直到2018年之前全球年度出版物数量稳定，之后显著增加。美国在研究产出方面领先（298篇文章），总被引次数最高（6565次）。哈佛大学是产出最多的机构（111篇文章），而《癫痫杂志》是产出最多的期刊（253篇文章）。关键词共现分析显示，研究重点从早期更多关注传统药物治疗，转向了近期更多关注基于大麻二酚的治疗、激光消融和迷走神经刺激。这项文献计量分析为小儿癫痫治疗研究的发展提供了新见解。它有助于展示过去20年该领域的主要贡献者，同时突出新出现的趋势。分析结果强调了研究重点从更传统的治疗方法转向研究替代疗法，包括基于大麻二酚的治疗、饮食干预、激光消融和迷走神经刺激。通过识别研究中的这些趋势并绘制作者合作网络，希望本研究能够为研究人员规划未来研究提供基础参考。
