Saka Bayaki, Teclessou Julienne Noude, Akakpo Sefako Abla, Pessinaba Soulemane, Gnossike Piham, Mahamadou Garba, Kassang Panawé, Mouhari-Toure Abas, Kombate Koussake, Pitché Palokinam
Service de Dermatolgie et IST, CHU Sylvanus Olympio, Université de Lomé, BP. 30785, Lome, Togo.
Service de Dermatolgie et IST, CHU Campus Université de Lomé, Lome, Togo.
BMC Res Notes. 2020 Sep 14;13(1):431. doi: 10.1186/s13104-020-05274-0.
The aim of this case-control study was to look for an association between hypertension and acne keloidalis nuchae (AKN) in black subjects.
We recruited 303 consenting subjects comprising 101 patients with AKN and 202 controls, case-matched by age (± 5 years). The mean patients age was 34.9 ± 10.7 years versus 35.6 ± 11.2 years for controls. The average duration of AKN progression in cases prior to consultation was 1831 days (5 years). The most frequently observed AKN lesions were papules (73/101; 72.3%), fibrous scars (42/101; 41.6%) and folliculitis/pustules (41/101; 40.6%). In terms of quality of life, the mean score of dermatology life quality index was 8.3 ± 5.2 (extremes: 0 to 22). In multivariate analysis, having a BMI of 25 kg/m or more (OR = 4.91; p < 0.001) and having systolic hypertension (OR = 1.22; p = 0.010) were associated with AKN.
本病例对照研究旨在探寻黑人受试者中高血压与颈部瘢痕疙瘩性痤疮（AKN）之间的关联。
我们招募了303名受试者，其中包括101例AKN患者和202名对照，按年龄（±5岁）进行病例匹配。患者的平均年龄为34.9±10.7岁，对照为35.6±11.2岁。病例在就诊前AKN进展的平均时长为1831天（5年）。最常观察到的AKN皮损为丘疹（73/101；72.3%）、纤维瘢痕（42/101；41.6%）和毛囊炎/脓疱（41/101；40.6%）。在生活质量方面，皮肤病生活质量指数的平均得分为8.3±5.2（范围：0至22）。多因素分析显示，体重指数（BMI）达到或超过25kg/m（比值比[OR]=4.91；p<0.001）以及患有收缩期高血压（OR=1.22；p=0.010）与AKN相关。
