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日本工厂工人胃及十二指肠溃疡的影响因素。一项病例对照研究。

The factors affecting gastric and duodenal ulcers in Japanese factory workers. A case-control study.

作者信息

Araki S

出版信息

Sangyo Igaku. 1985 Jul;27(4):242-7. doi: 10.1539/joh1959.27.242.

DOI:10.1539/joh1959.27.242
PMID:4079107
Abstract

Factors affecting gastric and duodenal ulcers in factory workers were examined by a case-control study of 74 male cases of active and inactive ulcers and in the same number of control subjects by the use of our past study materials. The cases were found by mass surveys for gastrointestinal disease over a period of four years at a plastics processing factory with 348 male workers; the controls were workers at the same factory in whom no ulcers were diagnosed in the surveys and were matched to each case by sex (all males), age (same 5-year span), type of work and job position. The results indicated that a) smoking was a major factor in gastric ulcers, and b) existence of ulcers in first or second degree relatives and eating at irregular intervals were two major factors for duodenal ulcers. Psychosocial factors such as frustration at work and in the family were not significantly associated with either gastric or duodenal ulcers. In the light of these findings, it was suggested that workers should be encouraged to refrain from smoking and to eat at regular intervals in order to prevent and recover from gastric and duodenal ulcers.

摘要

通过一项病例对照研究,利用我们过去的研究资料,对74例患有活动期和非活动期胃溃疡及十二指肠溃疡的男性工人病例以及相同数量的对照对象进行了调查,以探究影响工厂工人患胃溃疡和十二指肠溃疡的因素。这些病例是在一家有348名男性工人的塑料加工厂进行的为期四年的胃肠道疾病大规模调查中发现的;对照对象是在同一家工厂工作且在调查中未被诊断出患有溃疡的工人,他们在性别(均为男性)、年龄(相同的5年跨度)、工作类型和职位方面与每个病例相匹配。结果表明:a)吸烟是胃溃疡的主要因素;b)一级或二级亲属中有溃疡病史以及饮食不规律是十二指肠溃疡的两个主要因素。工作和家庭中的挫折感等社会心理因素与胃溃疡或十二指肠溃疡均无显著关联。鉴于这些发现,建议鼓励工人戒烟并规律饮食,以预防和治愈胃溃疡及十二指肠溃疡。

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引用本文的文献

1
No association of coffee consumption with gastric ulcer, duodenal ulcer, reflux esophagitis, and non-erosive reflux disease: a cross-sectional study of 8,013 healthy subjects in Japan.在日本,一项纳入 8013 例健康受试者的横断面研究显示,咖啡摄入与胃溃疡、十二指肠溃疡、反流性食管炎和非糜烂性反流病均无关。
PLoS One. 2013 Jun 12;8(6):e65996. doi: 10.1371/journal.pone.0065996. Print 2013.