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我的做法:用于脉动流条件下逼真显微外科训练的简易临时脉动泵模型。

How I do it: simple ad-hoc pulsatile pump model for realistic microsurgical training under pulsatile flow.

作者信息

Parvin Richard, El-Hajj Victor Gabriel, Staartjes Victor E, Ricciardi Luca, Gandia-Gonzalez Marisa, Feijoo Pablo Garcia, Núñez Mateo Tomas Fariña

机构信息

Neuro- and Spine Center, Hirslanden Klinik St. Anna, St. Annastrasse 32, Lützelmatt 3, 6006, Lucerne, Switzerland.

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

出版信息

Acta Neurochir (Wien). 2025 Aug 13;167(1):220. doi: 10.1007/s00701-025-06608-2.

DOI:10.1007/s00701-025-06608-2
PMID:40802064
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12350533/
Abstract

BACKGROUND

This simple pulsatile pump model (PPM) provides a realistic and low-cost model for microsurgical training. In this manner, the use of live animals for realistic microsurgical training is reduced, as it is possible to combine our model with several artificial microsurgical training models while retaining pulsatile flow.

METHOD

We detail steps for construction of the PPM for realistic microsurgical training under pulsatile flow - as well as microsurgical training examples - in a tried-and-true, cost-effective fashion, from readily available monitoring and infusion materials. The PPM is prepared by assembling a closed-loop system with two pressure applicators (infusion pumps/infusomats), a monitoring set connected to a transducer and display, and various infusion components (two intravenous drip/intrafix sets, saline, three-way stopcocks/discofix C, Heidelberger extension line, and pressure bags), allowing for adjustable pulsation frequency, flow and pressure as well as continuous pressure monitoring. The PPM can be used for a variety of microsurgical tasks, including microvascular repair and anastomosis and aneurysm clipping, providing a realistic and controlled animal-free training environment.

CONCLUSION

This model enables near-realistic microsurgical training under adjustable pulsatile flow based on readily available materials.

摘要

背景

这种简单的搏动泵模型(PPM)为显微外科训练提供了一个逼真且低成本的模型。通过这种方式,减少了使用活体动物进行逼真显微外科训练的情况,因为可以将我们的模型与多种人工显微外科训练模型相结合,同时保持搏动血流。

方法

我们详细介绍了以一种经过实践检验且经济高效的方式构建用于搏动血流下逼真显微外科训练的PPM的步骤以及显微外科训练示例,所使用的材料均易于获取,包括监测和输液材料。PPM是通过组装一个闭环系统来制备的,该系统包括两个压力施加器(输液泵/输液仪)、一个连接到传感器和显示器的监测装置以及各种输液组件(两个静脉滴注/内固定装置、生理盐水、三通旋塞/盘式固定器C、海德堡延长管和压力袋),可实现脉动频率、流量和压力的调节以及连续压力监测。PPM可用于多种显微外科任务,包括微血管修复与吻合以及动脉瘤夹闭,提供了一个逼真且可控的无动物训练环境。

结论

该模型能够基于易于获取的材料在可调节的搏动血流下进行近乎逼真的显微外科训练。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eca9/12350533/86a0a63e57a1/701_2025_6608_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eca9/12350533/f552ac0bb209/701_2025_6608_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eca9/12350533/08c706fcf640/701_2025_6608_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eca9/12350533/e4a4355fb077/701_2025_6608_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eca9/12350533/86a0a63e57a1/701_2025_6608_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eca9/12350533/f552ac0bb209/701_2025_6608_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eca9/12350533/08c706fcf640/701_2025_6608_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eca9/12350533/e4a4355fb077/701_2025_6608_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eca9/12350533/86a0a63e57a1/701_2025_6608_Fig4_HTML.jpg

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本文引用的文献

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Beyond Classic Anastomoses Training Models: Overview of Aneurysm Creation in Rodent Vessel Model.超越经典吻合训练模型:啮齿动物血管模型中动脉瘤创建的概述
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Acta Neurochir (Wien). 2020 Oct;162(10):2313-2321. doi: 10.1007/s00701-020-04522-3. Epub 2020 Aug 11.
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Microsurgical training using a pulsatile membrane pump and chicken thigh: a new, realistic, practical, nonliving educational model.
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