Sabljić Viktorija, Božić Dorotea, Aličić Damir, Ardalić Žarko, Olić Ivna, Bonacin Damir, Žaja Ivan
Institute of Emergency Medicine of Šibenik-Knin County, Narodnog Preporoda 1, 22000 Šibenik, Croatia.
Department of Gastroenterology and Hepatology, University Hospital Split, Spinčićeva 1, 21000 Split, Croatia.
J Clin Med. 2025 Aug 2;14(15):5448. doi: 10.3390/jcm14155448.
Pneumatic dilation (PD) is a widely used treatment modality in the management of achalasia. It is particularly relevant in regions where many centers lack access to advanced therapeutic modalities. Therefore, we aimed to assess the effectiveness and safety of PD in our local region. : This study retrospectively analyzed patients with achalasia that underwent PD from 1/2013 to 12/2019. The diagnosis of achalasia was established on the grounds of clinical symptoms, radiological and endoscopic findings, and esophageal manometry. Data on patient's clinical characteristics, dilation technique and postprocedural follow-up were collected and statistically analyzed. Procedure effectiveness was defined as the postprocedural Eckardt score ≤ 3. : PD significantly reduced frequency of dysphagia, regurgitation, and retrosternal pain ( < 0.001). Body-weight increased significantly one month and one year after the procedure ( < 0.001). The procedural success rate was 100%. No severe complications were reported. : PD is an effective and safe treatment modality in the management of achalasia. The study limitations include a single center design with the small number of participants, not all of whom underwent manometry, gender disproportion, absence of non-responders, and a short follow-up.
气囊扩张术（PD）是贲门失弛缓症治疗中一种广泛应用的治疗方式。在许多中心无法获得先进治疗手段的地区，它尤为重要。因此，我们旨在评估PD在我们当地的有效性和安全性。：本研究回顾性分析了2013年1月至2019年12月接受PD治疗的贲门失弛缓症患者。贲门失弛缓症的诊断基于临床症状、放射学和内镜检查结果以及食管测压。收集患者的临床特征、扩张技术和术后随访数据并进行统计学分析。手术有效性定义为术后埃卡德特评分≤3。：PD显著降低了吞咽困难、反流和胸骨后疼痛的发生率（<0.001）。术后1个月和1年体重显著增加（<0.001）。手术成功率为100%。未报告严重并发症。：PD是贲门失弛缓症治疗中一种有效且安全的治疗方式。研究局限性包括单中心设计、参与者数量少、并非所有患者都进行了测压、性别不均衡、缺乏无反应者以及随访时间短。
