Bolatkyzy Nazerke, Shepilov Daniil, Turmanov Rakhymzhan, Berillo Dmitriy, Vassilina Tursunay, Ibragimova Nailya, Berganayeva Gulzat, Dyusebaeva Moldyr
Faculty of Chemistry and Chemical Technology, Al-Farabi Kazakh National University, 71 Al-Farabi Avenue, Almaty 050042, Kazakhstan.
Department of Chemistry, Abai Kazakh National Pedagogical University, Dostyk Avenue 13, Almaty 050010, Kazakhstan.
Molecules. 2025 Aug 6;30(15):3281. doi: 10.3390/molecules30153281.
Skin disorders are common and often chronic conditions with significant therapeutic challenges. Limitations of conventional treatments, such as adverse effects and antimicrobial resistance, have increased interest in plant-based alternatives. This article presents the phytochemical composition and pharmacological potential of several medicinal plants traditionally used in the treatment of skin diseases, including , , , and . Based on an analysis of scientific literature, the presence of bioactive compounds-including flavonoids, anthocyanins, phenolic acids, tannins, and sesquiterpenes-is summarized, along with their antioxidant, anti-inflammatory, and antimicrobial effects. Emphasis is placed on the correlation between traditional ethnomedicinal applications and pharmacological mechanisms. The findings support the potential of these species as sources for dermatological phytotherapeutics. Further research is needed to standardize active constituents, assess safety, and conduct clinical validation.
皮肤疾病很常见，且往往是具有重大治疗挑战的慢性疾病。传统治疗方法存在局限性，如副作用和抗菌耐药性，这使得人们对基于植物的替代疗法越来越感兴趣。本文介绍了几种传统上用于治疗皮肤病的药用植物的植物化学成分和药理潜力，包括[此处列举植物名称，但原文未给出具体名称]。基于对科学文献的分析，总结了生物活性化合物的存在情况，包括黄酮类化合物、花青素、酚酸、单宁和倍半萜，以及它们的抗氧化、抗炎和抗菌作用。重点强调了传统民族医学应用与药理机制之间的相关性。这些发现支持了这些物种作为皮肤病植物疗法来源的潜力。需要进一步研究来规范活性成分、评估安全性并进行临床验证。
