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不可降解聚合物(聚醚醚酮)在个性化骨科中的应用——综述文章

The Use of Non-Degradable Polymer (Polyetheretherketone) in Personalized Orthopedics-Review Article.

作者信息

Wielgus Gabriela, Kajzer Wojciech, Kajzer Anita

机构信息

Department of Biomaterials and Medical Devices Engineering, Faculty of Biomedical Engineering, Silesian University of Technology, Roosevelta 40 Street, 41-800 Zabrze, Poland.

出版信息

Polymers (Basel). 2025 Aug 7;17(15):2158. doi: 10.3390/polym17152158.

DOI:10.3390/polym17152158
PMID:40808206
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12349293/
Abstract

Polyetheretherketone (PEEK) is a semi-crystalline thermoplastic polymer which, due to its very high mechanical properties and high chemical resistance, has found application in the automotive, aerospace, chemical, food and medical (biomedical engineering) industries. Owing to the use of additive technologies, particularly the Fused Filament Fabrication (FFF) method, this material is the most widely used plastic to produce skull reconstruction implants, parts of dental implants and orthopedic implants, including spinal, knee and hip implants. PEEK enables the creation of personalized implants, which not only have greater elasticity compared to implants made of metal alloys but also resemble the physical properties of the cortical layer of human bone in terms of their mechanical properties. Therefore, the aim of this article is to characterize polyether ether ketone as an alternative material used in the manufacturing of implants in orthopedics and dentistry.

摘要

聚醚醚酮(PEEK)是一种半结晶热塑性聚合物,由于其具有非常高的机械性能和高化学抗性,已在汽车、航空航天、化工、食品和医疗(生物医学工程)行业得到应用。由于增材制造技术的使用,特别是熔融长丝制造(FFF)方法,这种材料是生产颅骨重建植入物、牙科植入物部件和骨科植入物(包括脊柱、膝盖和髋关节植入物)最广泛使用的塑料。PEEK能够制造个性化植入物,这些植入物不仅比金属合金制成的植入物具有更大的弹性,而且在机械性能方面类似于人类骨骼皮质层的物理特性。因此,本文的目的是将聚醚醚酮作为一种用于骨科和牙科植入物制造的替代材料进行特性描述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143a/12349293/e3c9aada0c5a/polymers-17-02158-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143a/12349293/82e51f9d7337/polymers-17-02158-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143a/12349293/03f922a733ee/polymers-17-02158-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143a/12349293/c2bf528c17f7/polymers-17-02158-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143a/12349293/8e8c3056494a/polymers-17-02158-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143a/12349293/e3c9aada0c5a/polymers-17-02158-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143a/12349293/82e51f9d7337/polymers-17-02158-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143a/12349293/03f922a733ee/polymers-17-02158-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143a/12349293/c2bf528c17f7/polymers-17-02158-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143a/12349293/8e8c3056494a/polymers-17-02158-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/143a/12349293/e3c9aada0c5a/polymers-17-02158-g005.jpg

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Heliyon. 2024 Mar 5;10(5):e27328. doi: 10.1016/j.heliyon.2024.e27328. eCollection 2024 Mar 15.
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Cureus. 2023 Aug 29;15(8):e44307. doi: 10.7759/cureus.44307. eCollection 2023 Aug.
3
Design of customized implants and 3D printing of symmetric and asymmetric cranial cavities.
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J Mech Behav Biomed Mater. 2023 Oct;146:106061. doi: 10.1016/j.jmbbm.2023.106061. Epub 2023 Aug 3.
4
Polyetheretherketone development in bone tissue engineering and orthopedic surgery.聚醚醚酮在骨组织工程和骨科手术中的发展。
Front Bioeng Biotechnol. 2023 Jun 29;11:1207277. doi: 10.3389/fbioe.2023.1207277. eCollection 2023.
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Biomaterials as Implants in the Orthopedic Field for Regenerative Medicine: Metal versus Synthetic Polymers.用于再生医学的骨科领域植入物用生物材料:金属与合成聚合物
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