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免疫组织化学:婴儿肌纤维母细胞瘤诊断与管理中不可或缺的辅助手段。

Immunohistochemistry: An indispensable aid in diagnosis and management of infantile myofibroblastoma.

作者信息

Hegde Usha, Sheshanna Sreeshyla Huchanahalli, Doddawad Vidya Gowdappa, Nitin Priyanka

机构信息

Department of Oral Pathology and Microbiology, JSS Dental College and Hospital, A Constituent College of JSS AHER, Mysuru, Karnataka, India.

出版信息

J Oral Maxillofac Pathol. 2021 Sep-Dec;25(3):558. doi: 10.4103/jomfp.jomfp_388_20. Epub 2022 Jan 11.

Abstract

Myofibroma is a benign tumor of myofibroblasts occurring commonly in infants and children. It can occur as a solitary lesion or as multiple lesions in the soft tissues or intraosseously. The presence of the solitary lesion is common in the soft tissues of the head-and-neck region but rare in jawbones. Histologically, it has a biphasic pattern of presentation and mimics spindle cell tumors. Immunohistochemistry is essential for its confirmatory diagnosis. This article describes a case of this rare lesion presenting as a solitary lesion in the left body of the mandible in a 7-month-old boy baby. The diagnostic and therapeutic challenges have been discussed.

摘要

肌纤维瘤是一种由肌成纤维细胞构成的良性肿瘤,常见于婴幼儿。它可表现为孤立性病变,也可在软组织或骨内呈多发性病变。孤立性病变常见于头颈部软组织,但在颌骨中罕见。组织学上,它具有双相性表现模式,类似梭形细胞瘤。免疫组织化学对其确诊至关重要。本文描述了一例7个月大男婴下颌骨左侧体部出现孤立性病变的这种罕见病例。文中讨论了诊断和治疗方面的挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4a16/8859575/88fd29370ae7/JOMFP-25-558b-g001.jpg

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