Khan Nimra, Dileep Nandni
Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan.
J Diabetes. 2025 Aug;17(8):e70146. doi: 10.1111/1753-0407.70146.
This commentary discusses the study "Sleep Phenotypes, Genetic Susceptibility, and Risk of Obesity in Patients with Type 2 Diabetes: A National Prospective Cohort Study" by Xi et al. The study provides a perceptive investigation of how metabolic characteristics and genetic variables interact to affect body mass index (BMI) in people with T2D. It has some limitations, including reliance on self-reported sleep data and lack of in-depth sleep quality assessment. We highlight the importance of objective sleep data, detailed assessments of sleep quality, and advanced polygenic risk models in future research to better understand these relationships and inform precision diabetes care.
这篇评论讨论了Xi等人发表的研究“2型糖尿病患者的睡眠表型、遗传易感性与肥胖风险：一项全国前瞻性队列研究”。该研究对代谢特征和遗传变量如何相互作用以影响2型糖尿病患者的体重指数（BMI）进行了深刻的调查。它存在一些局限性，包括依赖自我报告的睡眠数据以及缺乏深入的睡眠质量评估。我们强调在未来研究中客观睡眠数据、详细的睡眠质量评估以及先进的多基因风险模型的重要性，以便更好地理解这些关系并为精准糖尿病护理提供依据。
