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-based screening of herbal compounds targeting FOXO signaling pathway in type 2 diabetes mellitus.

作者信息

Mudjahid Mukarram, Latada Nadila Pratiwi, Ophinni Youdiil, Nainu Firzan

机构信息

Department of Pharmacy, Faculty of Pharmacy, Hasanuddin University, Makassar, Indonesia.

Unhas Fly Research Group, Faculty of Pharmacy, Hasanuddin University, Makassar, Indonesia.

出版信息

Front Pharmacol. 2025 Jul 31;16:1621414. doi: 10.3389/fphar.2025.1621414. eCollection 2025.

DOI:10.3389/fphar.2025.1621414
PMID:40822472
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12350458/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/984b/12350458/608b8175afbb/fphar-16-1621414-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/984b/12350458/608b8175afbb/fphar-16-1621414-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/984b/12350458/608b8175afbb/fphar-16-1621414-g001.jpg

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本文引用的文献

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Exploring the antidiabetic potential of Sulawesi ethnomedicines: A study of and in a model of hyperglycemia.探索苏拉威西民族药物的抗糖尿病潜力：在高血糖模型中对[具体药物1]和[具体药物2]的研究
Narra J. 2025 Apr;5(1):e1712. doi: 10.52225/narra.v5i1.1712. Epub 2025 Jan 20.
2
Type 2 Diabetes Mellitus: New Pathogenetic Mechanisms, Treatment and the Most Important Complications.2型糖尿病：新的发病机制、治疗方法及最重要的并发症
Int J Mol Sci. 2025 Jan 27;26(3):1094. doi: 10.3390/ijms26031094.
3
Exploring the versatility of as a model organism in biomedical research: a comprehensive review.
探索[未提及具体生物]作为生物医学研究模式生物的多功能性：一项综合综述。 （注：原文中“Exploring the versatility of as a model organism”这里缺少具体所指生物）
Fly (Austin). 2025 Dec;19(1):2420453. doi: 10.1080/19336934.2024.2420453. Epub 2024 Dec 25.
4
as a Model for Human Disease: Insights into Rare and Ultra-Rare Diseases.作为人类疾病模型：对罕见病和超罕见病的见解
Insects. 2024 Nov 6;15(11):870. doi: 10.3390/insects15110870.
5
Sex-specific pharmacokinetic response to phytoestrogens in Drosophila melanogaster.黑腹果蝇中植物雌激素的性别特异性药代动力学反应。
Biomed Pharmacother. 2024 Jun;175:116612. doi: 10.1016/j.biopha.2024.116612. Epub 2024 Apr 24.
6
Betulinic Acid Increases the Lifespan of via Sir2 and FoxO Activation.桦木酸通过 Sir2 和 FoxO 的激活来延长寿命。
Nutrients. 2024 Feb 1;16(3):441. doi: 10.3390/nu16030441.
7
FoxO1 as a tissue-specific therapeutic target for type 2 diabetes.FoxO1 作为 2 型糖尿病的组织特异性治疗靶点。
Front Endocrinol (Lausanne). 2023 Oct 23;14:1286838. doi: 10.3389/fendo.2023.1286838. eCollection 2023.
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as a Translational Model System to Explore the Impact of Phytochemicals on Human Health.作为探索植物化学物质对人类健康影响的转化模型系统。
Int J Mol Sci. 2023 Aug 29;24(17):13365. doi: 10.3390/ijms241713365.
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Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050: a systematic analysis for the Global Burden of Disease Study 2021.全球、地区和国家 1990 年至 2021 年糖尿病负担，以及对 2050 年患病率的预测：2021 年全球疾病负担研究的系统分析。
Lancet. 2023 Jul 15;402(10397):203-234. doi: 10.1016/S0140-6736(23)01301-6. Epub 2023 Jun 22.
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Front Endocrinol (Lausanne). 2023 Mar 23;14:1143067. doi: 10.3389/fendo.2023.1143067. eCollection 2023.