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通过综合心理和营养干预优化结直肠癌患者的术后恢复

Optimizing postoperative recovery in colorectal cancer patients through integrated psychological and nutritional interventions.

作者信息

Wang Gang, Pan Shengjie

机构信息

Department of General Surgery, The First Affiliated Hospital of Soochow University, 899 Pinghai Road, Suzhou City, Jiangsu, 215006, P.R. China.

Department of Neurology, The First Affiliated Hospital of Soochow University, 899 Pinghai Road, Suzhou City, Jiangsu, 215006, P.R. China.

出版信息

J Cancer Surviv. 2025 Aug 23. doi: 10.1007/s11764-025-01883-5.

Abstract

OBJECTIVE

This study evaluates the effects of combined psychological intervention and enhanced nutritional support on postoperative recovery in CRC patients, focusing on nutritional status, sleep quality, pain management, psychological well-being, and quality of life.

METHODS

A randomized controlled trial was conducted at the First Affiliated Hospital of Soochow University from August 2021 to August 2023. A total of 300 CRC patients who underwent surgery were randomly assigned to the observation group (150 patients), receiving standard postoperative care plus psychological intervention and enhanced nutritional support, or the control group (150 patients), receiving standard care only. Primary outcomes included nutritional status (weight, serum albumin, total protein), sleep quality (Pittsburgh Sleep Quality Index), pain (Visual Analog Scale), psychological status (Self-Rating Anxiety and Depression Scales), and quality of life (EORTC QLQ-C30).

RESULTS

The observation group showed significant improvements in nutritional status, with higher serum albumin, total protein, prealbumin, and transferrin, along with increased body weight (P < 0.05). Sleep quality improved, with significantly lower PSQI scores (P < 0.05). Pain management was more effective, reflected by lower VAS scores (P < 0.05). Psychological assessments revealed reduced anxiety and depression, with lower SAS and SDS scores (P < 0.05). The observation group also had higher EORTC QLQ-C30 scores, indicating better quality of life (P < 0.05).

CONCLUSION

Psychological intervention combined with enhanced nutritional support significantly improves postoperative recovery in CRC patients by enhancing nutritional status, sleep quality, pain management, and psychological well-being. This integrated approach may serve as an effective strategy for CRC rehabilitation.

IMPLICATIONS FOR CANCER SURVIVORS

Integrating psychological support with enhanced nutritional care significantly improves recovery, quality of life, and emotional wellbeing after colorectal cancer surgery. For survivors, this highlights the importance of comprehensive supportive interventions that address both physical and psychological needs in routine survivorship care.

摘要

目的

本研究评估心理干预与强化营养支持相结合对结直肠癌(CRC)患者术后恢复的影响,重点关注营养状况、睡眠质量、疼痛管理、心理健康和生活质量。

方法

2021年8月至2023年8月在苏州大学附属第一医院进行了一项随机对照试验。共有300例接受手术的CRC患者被随机分为观察组(150例患者),接受标准术后护理加心理干预和强化营养支持,或对照组(150例患者),仅接受标准护理。主要结局包括营养状况(体重、血清白蛋白、总蛋白)、睡眠质量(匹兹堡睡眠质量指数)、疼痛(视觉模拟量表)、心理状态(自评焦虑和抑郁量表)和生活质量(欧洲癌症研究与治疗组织QLQ-C30量表)。

结果

观察组营养状况显著改善,血清白蛋白、总蛋白、前白蛋白和转铁蛋白水平更高,体重增加(P<0.05)。睡眠质量改善,匹兹堡睡眠质量指数得分显著降低(P<0.05)。疼痛管理更有效,视觉模拟量表得分更低(P<0.05)。心理评估显示焦虑和抑郁减轻,焦虑自评量表和抑郁自评量表得分更低(P<0.05)。观察组欧洲癌症研究与治疗组织QLQ-C30量表得分也更高,表明生活质量更好(P<0.05)。

结论

心理干预与强化营养支持相结合可通过改善营养状况、睡眠质量、疼痛管理和心理健康,显著提高CRC患者的术后恢复。这种综合方法可能是CRC康复的有效策略。

对癌症幸存者的启示

将心理支持与强化营养护理相结合可显著改善结直肠癌手术后的恢复、生活质量和情绪健康。对于幸存者而言,这凸显了在常规生存护理中满足身体和心理需求的综合支持干预措施的重要性。

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