Sawicki Tomasz, Ruszkowska Monika, Danielewicz Anna, Niedźwiedzka Ewa, Arłukowicz Tomasz, Przybyłowicz Katarzyna E
Department of Human Nutrition, Faculty of Food Sciences, University of Warmia and Mazury in Olsztyn, Słoneczna 45F, 10-719 Olsztyn, Poland.
Department of Internal Medicine, School of Medicine, Collegium Medicum, University of Warmia and Mazury, 10-900 Olsztyn, Poland.
Cancers (Basel). 2021 Apr 22;13(9):2025. doi: 10.3390/cancers13092025.
This review article contains a concise consideration of genetic and environmental risk factors for colorectal cancer. Known risk factors associated with colorectal cancer include familial and hereditary factors and lifestyle-related and ecological factors. Lifestyle factors are significant because of the potential for improving our understanding of the disease. Physical inactivity, obesity, smoking and alcohol consumption can also be addressed through therapeutic interventions. We also made efforts to systematize available literature and data on epidemiology, diagnosis, type and nature of symptoms and disease stages. Further study of colorectal cancer and progress made globally is crucial to inform future strategies in controlling the disease's burden through population-based preventative initiatives.
这篇综述文章简要探讨了结直肠癌的遗传和环境风险因素。与结直肠癌相关的已知风险因素包括家族和遗传因素以及与生活方式和生态相关的因素。生活方式因素很重要,因为它有可能增进我们对该疾病的了解。缺乏体育锻炼、肥胖、吸烟和饮酒也可以通过治疗干预来解决。我们还努力将关于流行病学、诊断、症状类型和性质以及疾病阶段的现有文献和数据系统化。对结直肠癌的进一步研究以及全球取得的进展对于通过基于人群的预防举措为控制该疾病负担的未来策略提供信息至关重要。