Suleĭmanov S Sh, Denisov Iu P, Sergeev P V
Farmakol Toksikol. 1985 Nov-Dec;48(6):58-61.
The interaction of 3H-estradiol and 3H-corticosterone with plasmatic membranes of the rat uterine cells was investigated. It was revealed that accumulation of estradiol in plasmatic membranes was conditioned by two processes: by the binding with highly specific glycoprotein membrane structures and by estrogen diffusion into the lipid membrane phase. At the same time, accumulation of corticosterone is determined exclusively by its penetration into the lipid matrix of plasmatic membranes of the rat uterine cells.
研究了3H-雌二醇和3H-皮质酮与大鼠子宫细胞质膜的相互作用。结果表明,雌二醇在质膜中的积累受两个过程的影响:与高度特异性的糖蛋白膜结构结合以及雌激素扩散到脂质膜相中。与此同时,皮质酮的积累完全取决于其渗透到大鼠子宫细胞质膜的脂质基质中。