Agarwal Deepanshi, Singh Udai Pratap, Nagpal Rajni, Chaman Chandrakar, Gupta Shraddha, Tyagi Garima
Department of Conservative Dentistry and Endodontics, Kothiwal Dental College and Research Centre, Moradabad, Uttar Pradesh, India.
J Conserv Dent Endod. 2025 Aug;28(8):740-745. doi: 10.4103/JCDE.JCDE_306_25. Epub 2025 Aug 1.
Dental caries remains a global health concern. While various prophylactic agents, including probiotics and other compounds, have been used, the search for effective natural solutions continues. Herbal products are valued for their anticariogenic properties. Mouthwashes help prevent bad breath, decay, and dry mouth. NaF rinse aids remineralization. This study explores the safety and efficacy of mango twigs, orange peel, and coconut oil as sustainable alternatives.
This study aimed to compare the anticariogenic effects of sodium fluoride, xylitol, probiotics, and various herbal extracts on and .
A microbiological assay assessed the zone of inhibition against and using 120 agar plates divided into six groups (20 plates/group), each further split into two subgroups (10 plates each), based on the bacteria smeared. The antibacterial effects of mango twig extract, orange peel extract, coconut oil, xylitol, probiotics and 0.2% sodium fluoride were tested. Each extract (50 μl) was inoculated, incubated at 37°C for 72 h, and inhibition zones measured.
Analysis of variance with Tukey's test was used for analysis.
Extracts from orange peel and mango twigs had notable antibacterial activity, unlike VCO, probiotics, and xylitol, which showed little to no effect.
Within this study's limits, ethanolic orange peel extract showed the strongest antimicrobial effect, followed by 0.2% NaF, mango twig extract, VCO, probiotics, and xylitol in decreasing order.
龋齿仍然是一个全球关注的健康问题。虽然已经使用了各种预防剂,包括益生菌和其他化合物,但对有效天然解决方案的探索仍在继续。草药产品因其防龋特性而受到重视。漱口水有助于预防口臭、龋齿和口干。氟化钠漱口水有助于再矿化。本研究探索芒果枝、橙皮和椰子油作为可持续替代品的安全性和有效性。
本研究旨在比较氟化钠、木糖醇、益生菌和各种草药提取物对[具体对象]的防龋效果。
采用微生物学测定法,使用120个琼脂平板评估对[具体细菌]的抑菌圈,根据涂抹的细菌将平板分为六组(每组20个平板),每组再进一步分为两个亚组(每组10个平板)。测试了芒果枝提取物、橙皮提取物、椰子油、木糖醇、益生菌和0.2%氟化钠的抗菌效果。接种每种提取物(50μl),在37°C下孵育72小时,并测量抑菌圈。
采用方差分析和Tukey检验进行分析。
与几乎没有效果的椰子油、益生菌和木糖醇不同,橙皮和芒果枝的提取物具有显著的抗菌活性。
在本研究的范围内,乙醇提取的橙皮提取物显示出最强的抗菌效果,其次是0.2%氟化钠、芒果枝提取物、椰子油、益生菌和木糖醇,顺序依次递减。