Banavar Ravi Spoorthi, Nirupad Sudarshini, Chippagiri Prashanthi, Pandurangappa Rohit
School of Dentistry, International Medical University, No. 126, Jalan 19/155B, Bukit Jalil, Kuala Lumpur, Malaysia.
Oral Pathology, Dr. Syamala Reddy Dental College Hospital and Research Centre, SGR College Main Road, Marathahalli Post, Bangalore, Karnataka, India.
Int J Dent. 2017;2017:4921614. doi: 10.1155/2017/4921614. Epub 2017 Oct 19.
Many plants or herbs exhibit potent antimicrobial activity against various microorganisms. They have no side effects and presumably act against and modulate the factors that are crucial for microbial survival or their activity. is a pioneer bacteria implicated in dental caries. This study aims to evaluate the antimicrobial activity of garlic bulbs, pudina leaves, and mango and eucalyptus twig extracts on by evaluating their zone of inhibition and determining their minimum inhibitory concentration (MIC).
Microbiological assay (well diffusion method) to determine zone of inhibition against pure forms of was performed. The antibacterial effects of methanolic extracts of mango twigs, eucalyptus twigs, pudina leaves, and garlic bulbs were studied. Test compounds were further evaluated for their MIC.
Extracts derived from mango and eucalyptus twigs showed significant antibacterial effects at test concentrations. Pudina and garlic extracts did not show any significant antibacterial effects at similar concentrations. Upon further evaluation of the 2 positive compounds for their MIC, mango twigs demonstrated more antimicrobial potential than eucalyptus twigs at a lower concentration.
Our observations indicated that the mango twig extracts possess higher antibacterial effects against than other compounds at specific test concentration.
许多植物或草本植物对多种微生物具有强大的抗菌活性。它们没有副作用，可能作用于并调节对微生物存活或其活性至关重要的因素。变形链球菌是引发龋齿的主要细菌。本研究旨在通过评估大蒜鳞茎、薄荷叶片、芒果和桉树枝条提取物对变形链球菌的抑菌圈并确定其最低抑菌浓度（MIC），来评价它们的抗菌活性。
采用微生物学测定法（打孔扩散法）来确定对变形链球菌纯培养物的抑菌圈。研究了芒果枝条、桉树枝条、薄荷叶片和大蒜鳞茎的甲醇提取物的抗菌效果。对测试化合物进一步评估其最低抑菌浓度。
在测试浓度下，芒果和桉树枝条的提取物显示出显著的抗菌效果。在相似浓度下，薄荷和大蒜提取物未显示出任何显著的抗菌效果。对这两种有阳性结果的化合物进一步评估其最低抑菌浓度时，芒果枝条在较低浓度下比桉树枝条表现出更强的抗菌潜力。
我们的观察结果表明，在特定测试浓度下，芒果枝条提取物对变形链球菌的抗菌效果比其他化合物更高。
