Gallocchio Federica, Mancin Marzia, Boscolo Anzoletti Aurora, Angeletti Roberto, Biancotto Giancarlo, Fedrizzi Giorgio, Gasparini Mara, Angelone Barbara, Bontacchio Silvana, Di Millo Sabrina, Cito Francesca, Diletti Gianfranco, Arcangeli Giuseppe
Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell'Università, 10, 35020 Legnaro, Italy.
Istituto Zooprofilattico Sperimentale della Lombardia e Dell'Emilia Romagna, Via Antonio Bianchi, 7/9, 25124 Brescia, Italy.
Toxics. 2025 Aug 19;13(8):690. doi: 10.3390/toxics13080690.
This study investigates the concentrations and patterns of dioxins and dioxin-like PCBs (TEQ Diox+PCB-DL) and non-dioxin-like PCBs (PCB-NDL) in eels from Lake Garda, assessing their relationship with biometric and lipid parameters. TEQ Diox+PCB-DL levels ranged from 1.70 to 77.1 pg/g (median: 9.90 pg/g), while PCB-NDL levels spanned from 14.0 to 1620 ng/g (median: 65.5 ng/g). Significant, albeit low, correlations were found: length and weight were negatively correlated, and lipid content was positively correlated, with both contaminants. Multivariable regression confirmed length and lipid percentage as significant predictors, although the models explained a limited proportion of variance (R: 0.23 and 0.17). Classification-based analyses showed that irregularly contaminated eels were shorter and had a higher lipid content. Multinomial logistic regression supported these findings, but showed limited predictive accuracy (AUC = 0.63). Notably, 28 out of 90 samples exceeded the EU regulatory limit for TEQ Diox+PCB-DL, and several surpassed the threshold for PCB-NDL, highlighting potential public health risks. Given the lipophilic nature and toxicity of these compounds, continued monitoring is warranted. The findings underscore the need for broader environmental assessments to better understand pollutant dynamics and support regulatory actions, including the extended ban on eel fishing in the region.
本研究调查了加尔达湖鳗鱼中二噁英、类二噁英多氯联苯（TEQ Diox+PCB-DL）和非类二噁英多氯联苯（PCB-NDL）的浓度及分布模式，评估了它们与生物特征和脂质参数之间的关系。TEQ Diox+PCB-DL水平在1.70至77.1皮克/克之间（中位数：9.90皮克/克），而PCB-NDL水平在14.0至1620纳克/克之间（中位数：65.5纳克/克）。发现了显著但较低的相关性：体长和体重呈负相关，脂质含量与两种污染物均呈正相关。多变量回归证实体长和脂质百分比是显著的预测因子，尽管模型解释的方差比例有限（R分别为0.23和0.17）。基于分类的分析表明，受污染情况不规则的鳗鱼较短且脂质含量较高。多项逻辑回归支持了这些发现，但预测准确性有限（AUC = 0.63）。值得注意的是，90个样本中有28个超过了欧盟对TEQ Diox+PCB-DL的监管限值，还有几个超过了PCB-NDL的阈值，凸显了潜在的公共健康风险。鉴于这些化合物的亲脂性和毒性，有必要持续进行监测。研究结果强调需要进行更广泛的环境评估，以更好地了解污染物动态并支持监管行动，包括该地区延长鳗鱼捕捞禁令。
