Verzella G, Bagnasco G, Mangia A
J Chromatogr. 1985 Dec 6;349(1):83-9. doi: 10.1016/s0021-9673(00)90636-8.
A simple and accurate quantitative determination of aspartame (L-alpha-aspartyl-L-phenylalanine methyl ester), a new artificial sweetener, is described. The method, which is based on ion-pair high-performance liquid chromatography, allows the determination of aspartame in finished bulk and dosage forms, and the detection of a few related products at levels down to 0.1%.