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关于死后牙齿变粉的系统评价:法医学分类、诊断价值及分析方法

A Systematic Review About Postmortem Pink Teeth: Forensic Classification, Diagnostic Value, and Analysis Methods.

作者信息

Aquila Isabella, Gualtieri Saverio, Princi Aurora, Sacco Matteo Antonio

机构信息

Institute of Legal Medicine, Department of Medical and Surgical Sciences, University "Magna Graecia" of Catanzaro, 88100 Catanzaro, Italy.

出版信息

Diagnostics (Basel). 2025 Aug 20;15(16):2092. doi: 10.3390/diagnostics15162092.

Abstract

The phenomenon of pink teeth represents a notable observation in forensic science, although its interpretation remains complex and not directly attributable to a specific cause of death. This systematic review provides an updated and comprehensive overview of the morphological and histological mechanisms associated with this finding, with a focus on hemoglobin diffusion and pigment accumulation during putrefaction rather than on detailed biochemical pathways. Environmental conditions, especially high humidity and moderate temperatures, are identified as key facilitators. The synthesis of the available evidence, including case reports, observational series, and experimental studies, confirms that pink discoloration is primarily linked to postmortem hemoglobin diffusion following erythrocyte breakdown and release of heme groups into dentinal structures. This process occurs more frequently under conditions that preserve hemoglobin and facilitate its migration into dental tissues. Importantly, pink teeth have been documented across a wide spectrum of postmortem scenarios, such as hanging, drowning, carbon monoxide poisoning, and prolonged exposure to humid environments, indicating that their presence is neither pathognomonic nor exclusively associated with a specific cause of death. Assessment methods include semi-quantitative visual scoring systems (e.g., SPTC and SPTR), spectrophotometric assays, and histochemical analyses for hemoglobin derivatives. Recent advances in digital forensics, particularly micro-computed tomography and artificial intelligence-based segmentation, may further support the objective evaluation of chromatic dental changes. This review underscores the need for standardized approaches to the identification, classification, and analysis, both qualitative and quantitative, of pink teeth in medico-legal practice. Although not diagnostic in isolation, their systematic study enhances our understanding of decomposition processes and contributes supplementary interpretive data in forensic investigations.

摘要

牙齿粉红色现象是法医学中一项值得注意的观察结果,尽管对其解读仍然复杂,且不能直接归因于特定死因。本系统综述提供了与这一发现相关的形态学和组织学机制的最新全面概述,重点关注腐败过程中的血红蛋白扩散和色素积累,而非详细的生化途径。环境条件,尤其是高湿度和适中温度,被确定为关键促进因素。对包括病例报告、观察系列和实验研究在内的现有证据进行综合分析,证实牙齿粉红色变色主要与红细胞分解以及血红素基团释放到牙本质结构后死后血红蛋白扩散有关。在保存血红蛋白并促进其向牙齿组织迁移的条件下,这个过程更频繁发生。重要的是,在广泛的死后场景中都有牙齿粉红色的记录,如缢死、溺水、一氧化碳中毒以及长期暴露于潮湿环境,这表明牙齿粉红色的出现既不是特征性的,也不专门与特定死因相关。评估方法包括半定量视觉评分系统(如SPTC和SPTR)、分光光度测定法以及对血红蛋白衍生物的组织化学分析。数字法医学的最新进展,特别是微计算机断层扫描和基于人工智能的分割技术,可能会进一步支持对牙齿颜色变化的客观评估。本综述强调在法医学实践中需要采用标准化方法对牙齿粉红色进行识别、分类以及定性和定量分析。尽管牙齿粉红色本身并非诊断性依据,但对其进行系统研究能增进我们对尸体分解过程的理解,并为法医调查提供补充性解释数据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b394/12386073/ce9d1932c0bb/diagnostics-15-02092-g001.jpg

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