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四丁基铵十钨酸盐催化3-亚甲基异吲哚啉-1-酮与醇/醚通过氢原子转移过程进行氢烷基化/烷氧基化反应。

Tetrabutylammonium decatungstate-catalyzed hydroalkylation/alkoxylation of 3-methyleneisoindolin-1-ones with alcohols/ethers through hydrogen atom transfer process.

作者信息

Fu Han, Wang Feixia, Wu Ziyan, Xie Xiaoyu, Zhang Yicheng, Liu Jie, Wang Lei

机构信息

Key Laboratory of Green and Precise Synthetic Chemistry and Application, Ministry of Education, School of Chemistry and Chemical Engineering, Huaibei Normal University Huaibei Anhui 235000 P. R. China

Advanced Research Institute and Department of Chemistry, Taizhou University Taizhou Zhejiang 318000 P. R. China.

出版信息

RSC Adv. 2025 Aug 26;15(37):30285-30289. doi: 10.1039/d5ra05071e. eCollection 2025 Aug 22.

Abstract

A highly efficient tetrabutylammonium decatungstate (TBADT)-catalyzed synthesis of isoindolinones using activated alkenes and alcohols/ethers hydrogen atom transfer process was developed. A variety of functionalized isoindolinones were obtained in good yields with high selectivity and broad functional group tolerance.

摘要

开发了一种高效的四丁基铵十钨酸盐(TBADT)催化的使用活化烯烃和醇/醚的氢原子转移过程合成异吲哚啉酮的方法。以良好的产率、高选择性和广泛的官能团耐受性获得了各种官能化的异吲哚啉酮。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c65b/12378743/e44cb59ce4af/d5ra05071e-f1.jpg

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