Capiau Andreas, Kint Isaura, Mehuys Els, De Backer Tine, Somers Annemie, Boussery Koen
Pharmaceutical Care Unit, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000, Ghent, Belgium.
Department of Pharmacy, Ghent University Hospital, C. Heymanslaan 10, 9000, Ghent, Belgium.
Int J Clin Pharm. 2025 Aug 30. doi: 10.1007/s11096-025-01985-1.
Antithrombotic agents are considered as high-risk medications, particularly during the perioperative period, because of the increased risk of bleeding. Balancing bleeding and thrombosis risks is crucial in the context of invasive procedures. The specific role of community pharmacists (CPs) in perioperative antithrombotic management remains unclear.
This study aimed to explore the role of CPs in perioperative antithrombotic management, focusing on their experiences, and the barriers and facilitators to expand their involvement.
A qualitative study was conducted in Belgium between March and May 2024 using semi-structured, in-depth interviews with CPs. The Theoretical Domains Framework guided the development of the interview guide to ensure comprehensive coverage of relevant domains. Interviews were transcribed verbatim and analysed thematically using open and axial coding in NVivo 14 by two independent researchers. Participants were randomly sampled and recruited until no new themes were generated.
A total of 13 CPs (7 female; median age 48 years, IQR 34-58) participated in the in-depth interviews. Four key themes emerged: (i) current involvement of CPs in perioperative antithrombotic management, (ii) factors influencing CPs' role, (iii) aspirations and perceived opportunities for role expansion, and (iv) proposed strategies to optimise CPs' contributions. CPs described their current role as limited and mainly reactive, with their involvement typically occurring postoperatively. Reported barriers included insufficient knowledge of antithrombotic protocols, time constraints, inconsistent and non-transparent hospital guidelines, lack of access to relevant medical records, and difficulty reaching hospital-based prescribers. Facilitators included CPs' unique position to oversee a patient's full medication regimen, strong and trusted patient relationships, early post-discharge contact, and intrinsic motivation to contribute more actively. Participants expressed a desire for more proactive and collaborative involvement, supported by structured training. They also stressed the importance of clear, well-accessible guidelines that are as uniform as possible across hospitals. Lastly, they emphasised the need for better accessibility to prescribers to facilitate more effective communication.
CPs' role in perioperative antithrombotic management is currently limited, particularly preoperatively. Addressing identified barriers and implementing the suggested improvements could strengthen their role. Further research is needed to validate these findings and guide future interventions.
抗血栓药物被视为高风险药物,尤其是在围手术期,因为出血风险增加。在侵入性手术的背景下,平衡出血和血栓形成风险至关重要。社区药剂师(CPs)在围手术期抗血栓管理中的具体作用仍不明确。
本研究旨在探讨CPs在围手术期抗血栓管理中的作用,重点关注他们的经验以及扩大其参与度的障碍和促进因素。
2024年3月至5月在比利时进行了一项定性研究,采用半结构化深度访谈CPs。理论领域框架指导了访谈指南的制定,以确保全面涵盖相关领域。访谈逐字记录,并由两名独立研究人员在NVivo 14中使用开放编码和轴心编码进行主题分析。参与者随机抽样并招募,直到没有产生新的主题。
共有13名CPs(7名女性;年龄中位数48岁,四分位间距34 - 58)参与了深度访谈。出现了四个关键主题:(i)CPs目前在围手术期抗血栓管理中的参与情况,(ii)影响CPs作用的因素,(iii)角色扩展的愿望和感知机会,以及(iv)优化CPs贡献的建议策略。CPs将他们目前的角色描述为有限且主要是被动反应的,他们的参与通常发生在术后。报告的障碍包括对抗血栓方案的知识不足、时间限制、医院指南不一致且不透明、无法获取相关病历以及难以联系到医院的开处方者。促进因素包括CPs在监督患者完整药物治疗方案方面的独特地位、牢固且值得信赖的患者关系、出院后早期联系以及更积极贡献的内在动力。参与者表示希望在结构化培训的支持下进行更积极和协作的参与。他们还强调了清晰、易于获取且在各医院尽可能统一的指南的重要性。最后,他们强调需要更好地联系到开处方者以促进更有效的沟通。
CPs在围手术期抗血栓管理中的作用目前有限,尤其是在术前。解决已确定的障碍并实施建议的改进措施可以加强他们的作用。需要进一步研究来验证这些发现并指导未来的干预措施。