Pollard M, Luckert P H
Prostate. 1985;6(4):389-93. doi: 10.1002/pros.2990060407.
An adenocarcinoma of the prostate gland developed in one rat of the Lobund Sprague-Dawley (S-D) strain, following treatments with testosterone propionate in silastic membranes. The transplanted cells (PA-SD1) developed local tumors, metastasized through lymphatic channels to the lungs, and induced osteolytic lesions when deposited adjacent to the calvarium. In vitro-propagated PA-SD1 cells produced the same tumor type in Lobund strain S-D rats as that from which it was derived.
在Lobund斯普拉格-道利（S-D）品系的一只大鼠中，在用硅橡胶膜包埋丙酸睾酮处理后发生了前列腺腺癌。移植的细胞（PA-SD1）形成了局部肿瘤，通过淋巴管转移至肺部，并在沉积于颅盖骨附近时诱发溶骨性病变。体外培养扩增的PA-SD1细胞在Lobund品系的S-D大鼠中产生了与其来源相同类型的肿瘤。
