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内侧单髁膝关节置换失败中的冠状轴偏差:针对无菌性松动进行翻修的患者的影像学研究

Coronal axis deviations in medial unicompartmental knee arthroplasty failures: an imaging study of patients revised for aseptic loosening.

作者信息

Migliorini Filippo, Maffulli Nicola, Kämmer Daniel, Hofmann Ulf Krister, Eschweiler Jörg, Bell Andreas

机构信息

Department of Trauma and Reconstructive Surgery, University Hospital of Halle, Martin-Luther University Halle-Wittenberg, Ernst-Grube-Street 40, 06097, Halle (Saale), Germany.

Department of Orthopaedic and Trauma Surgery, Academic Hospital of Bolzano (SABES-ASDAA), Via Lorenz Böhler 5, 39100, Bolzano, Italy.

出版信息

Eur J Med Res. 2025 Sep 2;30(1):832. doi: 10.1186/s40001-025-03112-2.

Abstract

PURPOSE

Aseptic loosening remains a leading cause of revision in medial unicompartmental knee arthroplasty (UKA). This imaging study aimed to identify recurrent patterns of coronal alignment deviation in patients undergoing revision to total knee arthroplasty (TKA) to explore whether subtle malalignment may contribute to biomechanical failure.

METHODS

Imaging of patients who underwent revision surgery of a medial UKA to TKA for aseptic loosening of the tibial or femoral component was retrieved. Lower limb axes were evaluated using anteroposterior plain radiographs of the leg using the software MediCAD Knie 2D (mediCAD Hectec GmbH, Altdorf, Germany). The radiographic axes of revised patients were compared with established reference values, as defined by the MediCAD Knie 2D software and published literature, to identify common alignment patterns potentially associated with aseptic loosening.

RESULTS

Data from 62 patients were analysed. Before the revision surgery, the joint line convergence angle (JLCA, P = 0.002) and the anatomical-mechanical angle (AMA, P < 0.0001) were statistically significantly greater than the corresponding reference values. In contrast, the mechanical lateral distal femoral angle (mLDFA, P < 0.0001), the mechanical and anatomical medial proximal tibial angle (mMPTA and aMPTA, P < 0.0001), and the mechanical and anatomical lateral distal tibial angle (mLDTA and aLDTA, P < 0.0001) were significantly lower than reference. No statistically significant difference was found in the mechanical lateral proximal femoral angle (mLPFA, P = 0.9) or in the mechanical axis deviation (MAD, P = 0.5) when compared to normative data.

CONCLUSION

Our cohort of patients revised from medial UKA to TKA for aseptic loosening frequently exhibited consistent deviations in lower limb alignment, particularly increased AMA and JLCA, and reduced mLDFA, mMPTA, and mLDTA. These subtle but recurrent patterns may alter load distribution across the medial compartment, contributing to implant micromotion and loosening. A detailed preoperative axis assessment may help identify patients at a higher biomechanical risk.

摘要

目的

无菌性松动仍然是内侧单髁膝关节置换术(UKA)翻修的主要原因。这项影像学研究旨在确定接受全膝关节置换术(TKA)翻修的患者冠状面排列偏差的复发模式,以探讨细微的排列不齐是否可能导致生物力学失败。

方法

检索因胫骨或股骨组件无菌性松动而接受内侧UKA翻修至TKA手术患者的影像学资料。使用MediCAD Knie 2D软件(德国阿尔特多夫的mediCAD Hectec GmbH公司)通过腿部前后位X线平片评估下肢轴线。将翻修患者的X线轴线与MediCAD Knie 2D软件和已发表文献所定义的既定参考值进行比较,以确定可能与无菌性松动相关的常见排列模式。

结果

分析了62例患者的数据。在翻修手术前,关节线汇聚角(JLCA,P = 0.002)和解剖力学角(AMA,P < 0.0001)在统计学上显著大于相应的参考值。相比之下,机械性外侧股骨远端角(mLDFA,P < 0.0001)、机械性和解剖学内侧胫骨近端角(mMPTA和aMPTA,P < 0.0001)以及机械性和解剖学外侧胫骨远端角(mLDTA和aLDTA,P < 0.0001)显著低于参考值。与标准数据相比,机械性外侧股骨近端角(mLPFA,P = 0.9)或机械轴偏差(MAD,P = 0.5)未发现统计学上的显著差异。

结论

我们这组因无菌性松动从内侧UKA翻修至TKA的患者经常表现出下肢排列的一致偏差,特别是AMA和JLCA增加,以及mLDFA、mMPTA和mLDTA降低。这些细微但反复出现的模式可能会改变内侧间室的负荷分布,导致植入物微动和松动。详细的术前轴线评估可能有助于识别生物力学风险较高的患者。

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