Zhang Feng, Laidlaw Grace, Johnson Guy, McGregor Hugh, Ji Hongxiu, Yang Xiaoming
Image-Guided Bio-Molecular Intervention Research and Division of Interventional Radiology, Department of Radiology, University of Washington School of Medicine, Seattle, USA.
EngMedicine. 2025 Mar;2(1). doi: 10.1016/j.engmed.2024.100044. Epub 2024 Nov 25.
Intraluminal magnetic resonance imaging (MRI) is a promising option to guide interventions, offering several advantages over other imaging modalities. It provides high spatial and contrast resolution for imaging luminal structures, excellent extra-luminal soft tissue visualization, real-time tracking of interventional devices, and operates without ionizing radiation. The applications of intraluminal MRI range from high-resolution imaging of vessel walls to MRI-guided interventions for managing life-threatening conditions such as cardiovascular atherosclerotic disease and malignancies within luminal structures. Clinical use of intraluminal MR technology optimizes endovascular delivery of therapeutics to targeted vessel segments and guides myocardial delivery of stem cells. However, advancements are still required, such as the refinement of MR-compatible interventional devices, development of real-time "MR fluoroscopy" similar to X-ray fluoroscopy, and establishment of safe clinical environments with large bore and short magnets. These improvements are essential for broader clinical adoption of intraluminal MR technology in healthcare.
腔内磁共振成像（MRI）是一种很有前景的引导介入治疗的方法，与其他成像方式相比具有多个优势。它为管腔结构成像提供高空间分辨率和对比度分辨率，能出色地显示管腔外软组织，可实时跟踪介入器械，且无需电离辐射。腔内MRI的应用范围从血管壁的高分辨率成像到MRI引导的介入治疗，用于处理危及生命的疾病，如心血管动脉粥样硬化疾病和管腔结构内的恶性肿瘤。腔内MR技术的临床应用可优化治疗药物向目标血管段的血管内递送，并指导干细胞向心肌的递送。然而，仍需要取得进展，例如改进与MR兼容的介入器械、开发类似于X射线荧光透视的实时“MR荧光透视”，以及建立配备大孔径和短磁体的安全临床环境。这些改进对于腔内MR技术在医疗保健领域更广泛的临床应用至关重要。
