Dookie Richard L, Subrt Paul, Tschen Jaime
Clinical Documentation, Landmark Medical Center, Woonsocket, USA.
Dermatology, Katy Westside Dermatology, Houston, USA.
Cureus. 2025 Aug 27;17(8):e91086. doi: 10.7759/cureus.91086. eCollection 2025 Aug.
Eruptive pruritic papular porokeratosis (EPPP) is a rare inflammatory variant of disseminated superficial porokeratosis characterized by the sudden onset of pruritic papules, primarily affecting the extremities and trunk. We present the case of a 77-year-old male who developed EPPP without any underlying malignancy or immunosuppression. Histopathology confirmed EPPP, and the patient underwent treatment with topical lovastatin 2% ointment, followed by topical calcipotriene. This report highlights the clinical presentation, diagnostic workup, therapeutic interventions, and emerging insights into the management of this uncommon condition.
发疹性瘙痒性丘疹性汗孔角化症（EPPP）是播散性浅表性汗孔角化症的一种罕见炎症变体，其特征为瘙痒性丘疹突然发作，主要累及四肢和躯干。我们报告一例77岁男性患者，其患发疹性瘙痒性丘疹性汗孔角化症，无任何潜在恶性肿瘤或免疫抑制情况。组织病理学确诊为发疹性瘙痒性丘疹性汗孔角化症，该患者接受了2%局部用洛伐他汀软膏治疗，随后使用局部用卡泊三烯治疗。本报告重点介绍了这种罕见病症的临床表现、诊断检查、治疗干预措施以及管理方面的新见解。
