Evaluation of systemic immune inflammation index, HALP score, neutrophil-lymphocyte ratio and platelet-lymphocyte ratio in pediatric burned patients.

OBJECTIVES

To evaluate whether there is any relationship between neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio(PLO), systemic immune -inflammation (SII) level and HALP score and the location of involvement, surface width, burn degree in pediatric burn patients to investigate the effect on prognosis.

METHODS

After obtaining institutional ethical committee approval, a retrospective analysis was conducted on 192 pediatric cases (under 18 years old) treated for burns in our hospital from December 2018 to December 2023. Hemoglobin, leukocyte, neutrophil, platelet and albumin levels. Simultaneously NLR, PLR, SII and HALP scores were calculated.

RESULTS

Post-hoc test results revealed that the NLR values in the first-degree burn group were significantly lower than those in the second-degree burn group and the group with combined first- and second-degree burns (=0.001, =0.027). Similarly, the SII values in the first-degree burn group were significantly lower than those in the second-degree burn group and the combined burn group (=0.001, =0.004). The HALP score values in the combined burn group were significantly lower than those in the first-degree burn group (=0.031). No significant differences were observed between other groups (>0.05).

CONCLUSION

These parameters are derived from routinely collected blood tests, making them cost-effective, easily accessible, and practical for patients. Therefore, they could be useful as biomarkers for predicting prognosis in pediatric burned patients.