Khadka Chhetri Susmita, Ghimire Sinjin, Thapa Susant, Suraj K C, Khanal Bhawani, Agrawal Yamuna
Department of General Surgery, B P Koirala Institute of Health Sciences, Dharan, Nepal.
Department of Pathology, B P Koirala Institute of Health Sciences, Dharan, Nepal.
Ann Med Surg (Lond). 2025 Jul 14;87(9):6078-6082. doi: 10.1097/MS9.0000000000003568. eCollection 2025 Sep.
Desmoplastic fibroblastoma is a rare benign soft-tissue tumor which is typically painless and slow-growing, commonly found in the extremities. Despite its benign nature, recurrence is rare, and it generally shows favorable outcomes.
A 34-year-old male first noticed a painless, slow-growing mass on his left lower back 4 years ago. Two years ago, he underwent a wide local excision of the mass, which was diagnosed as desmoplastic fibroblastoma. However, the mass recurred and progressively enlarged over time. He presented again with the recurrent mass, which was excised a second time. Histopathological examination confirmed the recurrence of desmoplastic fibroblastoma.
Desmoplastic fibroblastoma usually has an excellent prognosis, with no reported recurrences. However, in this case, recurrence was observed, which is uncommon. The recurrence may be attributed to factors such as incomplete excision due to the tumor's difficult location or inherent biological characteristics of the tumor cells. This rare occurrence warrants further investigation into potential contributing factors for recurrence.
This case highlights the rare recurrence of desmoplastic fibroblastoma following initial excision. While the tumor generally has an excellent prognosis, this recurrence emphasizes the importance of long-term follow-up.
促纤维增生性纤维母细胞瘤是一种罕见的良性软组织肿瘤，通常无痛且生长缓慢，常见于四肢。尽管其性质为良性，但复发罕见，总体预后良好。
一名34岁男性4年前首次注意到左下腹有一个无痛、生长缓慢的肿块。两年前，他接受了该肿块的广泛局部切除，被诊断为促纤维增生性纤维母细胞瘤。然而，肿块复发并随时间逐渐增大。他再次因复发肿块就诊，再次接受了切除。组织病理学检查证实为促纤维增生性纤维母细胞瘤复发。
促纤维增生性纤维母细胞瘤通常预后良好，尚无复发报道。然而，本病例出现了复发，这种情况并不常见。复发可能归因于肿瘤位置特殊导致切除不完全或肿瘤细胞的固有生物学特性等因素。这种罕见情况值得进一步研究复发的潜在促成因素。
本病例凸显了促纤维增生性纤维母细胞瘤初次切除后罕见的复发情况。虽然该肿瘤总体预后良好，但此次复发强调了长期随访的重要性。
