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Recent progress in macrocyclic trichothecene research: structures, biosynthetic pathways, and biological activities.

作者信息

Yan Peiwen, Zhang Hui, Li Li

机构信息

Engineering Research Center of Industrial Microbiology (Ministry of Education), Fujian Normal University, Fuzhou, 350117, People's Republic of China.

College of Life Sciences, Fujian Normal University, Fuzhou, 350117, People's Republic of China.

出版信息

Arch Microbiol. 2025 Sep 4;207(10):249. doi: 10.1007/s00203-025-04454-5.

DOI:10.1007/s00203-025-04454-5
PMID:40906220
Abstract
摘要

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本文引用的文献

1
Biosynthesis of the Central Tricyclic Skeleton of Trichothecene Mycotoxins.
J Am Chem Soc. 2025 Mar 26;147(12):10331-10338. doi: 10.1021/jacs.4c16973. Epub 2025 Mar 11.
2
Neuroprotective trichothecene macrolides from Myrothecium roridum Q6, an endophytic fungus residing in Hypericum perforatum.
Fitoterapia. 2025 Apr;182:106454. doi: 10.1016/j.fitote.2025.106454. Epub 2025 Feb 25.
3
Macrocyclic trichothecenes from Myrothecium verrucaria PA 57 and their cytotoxic activity.麦角硫因环三肽类化合物及其细胞毒性研究。
Chin J Nat Med. 2024 Sep;22(9):854-863. doi: 10.1016/S1875-5364(24)60573-X.
4
Role of tri18 gene in Epiroridin E production and toxin resistance mechanisms in Paramyrothecium roridum.tri18 基因在疣孢漆斑菌产生埃辟罗菌素 E 和毒素抗性机制中的作用。
Int J Biol Macromol. 2024 Nov;280(Pt 2):135746. doi: 10.1016/j.ijbiomac.2024.135746. Epub 2024 Sep 16.
5
Correction: Cytotoxic trichothecene-type sesquiterpenes from the sponge-derived fungus with tyrosine kinase inhibition.更正：来自海绵衍生真菌的具有酪氨酸激酶抑制作用的细胞毒性单端孢霉烯型倍半萜。
RSC Adv. 2019 Jul 10;9(37):21518. doi: 10.1039/c9ra90052g. eCollection 2019 Jul 5.
6
Trichothecene macrolides from the endophytic fungus Paramyrothecium roridum and their cytotoxic activity.来源于内生真菌玫红拟青霉的多氧烯大环内酯类化合物及其细胞毒性活性。
Fitoterapia. 2020 Nov;147:104768. doi: 10.1016/j.fitote.2020.104768. Epub 2020 Nov 7.
7
Genetic bases for variation in structure and biological activity of trichothecene toxins produced by diverse fungi.真菌产生的多型性曲菌烯毒素的结构和生物活性变化的遗传基础。
Appl Microbiol Biotechnol. 2020 Jun;104(12):5185-5199. doi: 10.1007/s00253-020-10612-0. Epub 2020 Apr 23.
8
New tricks for old dogs: Two new macrocyclic trichothecene epimers and absolute configuration of 16-hydroxyverrucarin B.老狗有新把戏：两种新的大环曲菌素表鬼笔环肽及其 16-羟基疣孢菌素 B 的绝对构型。
Phytochemistry. 2020 Apr;172:112238. doi: 10.1016/j.phytochem.2019.112238. Epub 2020 Jan 10.
9
Antifungal Macrocyclic Trichothecenes from the Insect-Associated Fungus .昆虫共生真菌来源的抗真菌大环三萜烯
J Agric Food Chem. 2019 Nov 27;67(47):13033-13039. doi: 10.1021/acs.jafc.9b04507. Epub 2019 Nov 15.
10
Cytotoxic Trichothecene Macrolides Produced by the Endophytic Myrothecium roridum.内生拟盘多毛孢Myrothecium roridum 产生的细胞毒三萜大环内酯
J Nat Prod. 2019 Jun 28;82(6):1503-1509. doi: 10.1021/acs.jnatprod.8b01034. Epub 2019 May 22.