Kaveladze Benjamin, Voelkel Jan, Stagnaro Michael, Huang Mingjing, Smock Amanda, Sullivan Erin, Xu Yao, McCall Madison, Zapata Juan Pablo, Ishtiaque Syed, Bhattacharjee Ananya, Georgieva Iva, Hernandez-Ramos Rosa, Huber Kenneth, Jennings Julia, Kirk Arianna, Kornfield Rachel, Knowles Robert, Lind Monika, Liu Michelle, Liut Michael, Mariakakis Alex, Mattu Ali, McGuire Adam, Meyerhoff Jonah, Mrazek Alissa, Mrazek Michael, Mohr David, Morris Robert, Mosunic Christopher, Nip Hana, Olson-Urtecho Allen, Podell Jessa, Ransom Dustyn, Rizvi Shireen, Southward Matthew, Stoeckl Sarah Elizabeth, Taylor Madison, Texter Amy, Trotter Angelique, Tower Calvin, Williams Joseph, Woodson Elijah, Wislocki Katherine, Protzko John, Lorenzo-Luaces Lorenzo, Schueller Stephen, Nock Matthew, Schleider Jessica
University of California, Irvine, USA.
Cornell University.
Res Sq. 2025 Aug 25:rs.3.rs-7236847. doi: 10.21203/rs.3.rs-7236847/v1.
Digital self-guided single-session interventions (SSIs) provide a structured psychological intervention within one interaction. We crowdsourced 66 diverse 10-minute SSIs for depression and selected 11 for testing in a pre-registered "megastudy" (ClinicalTrials.gov ID: NCT06856668). American adults (N = 7,505) experiencing elevated depressive symptoms were recruited online and randomly assigned to one of the 11 crowdsourced SSIs, a previously-validated active comparison SSI, or a control without intervention content. Nearly all SSIs boosted agency and hope for improvement immediately after completion (ds ≤ 0.37). However, only two significantly reduced depression at four-week follow-up (ds = 0.14 and 0.15). Unexpectedly, some SSIs may have decreased readiness to change at four weeks (ds ≤ 0.14). The most successful SSIs provided focused, engaging, and actionable guidance on a skill that directly addressed users' struggles. Future work should aim to leverage SSIs' short-term gains to promote longer-term behavior change or service engagement.
数字化自助单节干预（SSIs）在一次互动中提供结构化心理干预。我们通过众包方式收集了66种针对抑郁症的不同的10分钟SSIs，并选择了11种在一项预先注册的“大型研究”（ClinicalTrials.gov标识符：NCT06856668）中进行测试。招募了有抑郁症状加剧的美国成年人（N = 7505），并将他们随机分配到11种众包的SSIs之一、一种先前验证过的有效对照SSI或无干预内容的对照组。几乎所有的SSIs在完成后立即增强了行动力和改善的希望（d值≤0.37）。然而，只有两种在四周随访时显著降低了抑郁水平（d值 = 0.（此处原文可能有误，推测应为0.14）和0.15）。出乎意料的是，一些SSIs在四周时可能降低了改变的意愿（d值≤0.14）。最成功的SSIs针对直接解决用户困扰的一项技能提供了有针对性、引人入胜且可行的指导。未来的工作应旨在利用SSIs的短期收益来促进长期行为改变或服务参与。
