Harach H R, Saravia Day E, Franssila K O
Am J Surg Pathol. 1985 Jul;9(7):525-30. doi: 10.1097/00000478-198507000-00007.
An apparently new tumor entity of the thyroid is reported. The tumor was histologically characterized by good demarcation, lobular pattern, keratin-positive spindle cells, glandular elements, stromal hyalinization, and calcifications. These findings are suggestive of a tumor related to spindle-cell thymoma and apparently closely related to the recently described entity, ectopic hamartomatous thymoma. The patient, a 23-year-old man is alive and well 10 years after diagnosis. Two histologically similar cases have earlier been reported in the English literature under the heading "malignant teratoma."
据报道,甲状腺出现了一种明显的新肿瘤实体。该肿瘤在组织学上的特征为边界清晰、小叶状结构、角蛋白阳性的梭形细胞、腺性成分、间质透明变性及钙化。这些发现提示该肿瘤与梭形细胞胸腺瘤有关,且显然与最近描述的异位错构瘤实体密切相关。该患者为一名23岁男性,诊断后10年仍健在且情况良好。在英文文献中,曾有两篇组织学相似的病例以“恶性畸胎瘤”为题早期报道过。