Flemming B, Roloff D
Biomed Biochim Acta. 1985;44(11-12):1687-704.
An extracorporeal veno-venous bypass utilizing an oxygenator to alter mixed venous blood gases was used in experiments on chloralose anesthetized cats. The gas mixture in the oxygenator was alternate 95% O2 or 95% N2 with additional 5% CO2. The produced difference of pO2 in the right ventricle (pO2v-) was 1.3 kPa. The arterial acid base status and the blood gases were not affected by this procedure. Comparing the alterations of pO2v- the higher level of pO2v- was connected with an increase of the mean arterial blood pressure, of the clearances of inulin and PAH, and of the sodium and the potassium excretion. These experiments demonstrate that the alterations of pO2v- have influence on the renal function.
在水合氯醛麻醉的猫身上进行的实验中，使用了一种利用氧合器改变混合静脉血气体的体外静脉-静脉旁路。氧合器中的气体混合物为交替的95%氧气或95%氮气，并额外添加5%二氧化碳。右心室中产生的pO2差异（pO2v-）为1.3kPa。该操作未影响动脉酸碱状态和血气。比较pO2v-的变化，较高水平的pO2v-与平均动脉血压、菊粉和对氨基马尿酸清除率以及钠和钾排泄的增加有关。这些实验表明，pO2v-的变化对肾功能有影响。
