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利用Detectron2在组织病理学图像中进行准确高效的结肠癌检测。

Utilizing Detectron2 for accurate and efficient colon cancer detection in histopathological images.

作者信息

Chen Luxi, Shen Jie, Li Xinyu, Li Rongzhou, Gao Xiaoyun, Chen Xinyue, Pan Xiaotian, Jin Xiaosheng

机构信息

Pediatric emergency observation department, The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

Ultrasound Imaging Department, The Third Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.

出版信息

Front Bioeng Biotechnol. 2025 Aug 22;13:1593534. doi: 10.3389/fbioe.2025.1593534. eCollection 2025.

Abstract

INTRODUCTION

Colon cancer ranks among the most prevalent and lethal cancers globally, emphasizing the urgent need for accurate and early diagnostic tools. Recent advances in deep learning have shown promise in medical image analysis, offering potential improvements in detection accuracy and efficiency.

METHODS

This study proposes a novel approach for classifying colon tissue images as normal or cancerous using Detectron2, a deep learning framework known for its superior object detection and segmentation capabilities. The model was adapted and optimized for histopathological image classification tasks. Training and evaluation were conducted on the LC25000 dataset, which contains 10,000 labeled images (5,000 normal and 5,000 cancerous).

RESULTS

The optimized Detectron2 model achieved an exceptional accuracy of 99.8%, significantly outperforming traditional image analysis methods. The framework demonstrated high computational efficiency and robustness in handling the complexity of medical image data.

DISCUSSION

These results highlight Detectron2's effectiveness as a powerful tool for computer-aided diagnostics in colon cancer detection. The approach shows strong potential for integration into clinical workflows, aiding pathologists in early diagnosis and contributing to improved patient outcomes. This study also illustrates the transformative impact of advanced machine learning techniques on medical imaging and cancer diagnostics.

摘要

引言

结肠癌是全球最常见且致命的癌症之一,这凸显了对准确和早期诊断工具的迫切需求。深度学习的最新进展在医学图像分析中显示出了前景,有望提高检测的准确性和效率。

方法

本研究提出了一种使用Detectron2将结肠组织图像分类为正常或癌性的新方法,Detectron2是一个以其卓越的目标检测和分割能力而闻名的深度学习框架。该模型针对组织病理学图像分类任务进行了调整和优化。在LC25000数据集上进行训练和评估,该数据集包含10000张标记图像(5000张正常图像和5000张癌性图像)。

结果

优化后的Detectron2模型实现了99.8%的卓越准确率,显著优于传统图像分析方法。该框架在处理医学图像数据的复杂性方面表现出高计算效率和鲁棒性。

讨论

这些结果突出了Detectron2作为结肠癌检测中计算机辅助诊断的强大工具的有效性。该方法显示出整合到临床工作流程中的强大潜力,有助于病理学家进行早期诊断并改善患者预后。本研究还说明了先进的机器学习技术对医学成像和癌症诊断的变革性影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f081/12411774/33c888393d7c/fbioe-13-1593534-g001.jpg

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