Pazdrowski Paweł, Król Oliwia, Linkiewicz Jan, Lizurej Wojciech, Moszyńska Marta, Szymoniak-Lipska Marta, Korecka Katarzyna
Clinical Hospital of Poznan University of Medical Sciences, Poznań, Poland.
Ministry of Internal Affairs Hospital in Poznan, Poznań, Poland.
Rep Pract Oncol Radiother. 2025 Aug 7;30(3):417-423. doi: 10.5603/rpor.106158. eCollection 2025.
Currently, photodynamic therapy (PDT) is widely used, mainly in treatment of actinic keratosis (AK), especially grades I and II following the Olsen classification. The main side effects include burning, stinging, and pain during irradiation. Alternative protocols include daylight PDT (dPDT), which uses sunlight instead of artificial light after applying a photosensitizer. Unlike conventional PDT, daylight therapy is less painful and more comfortable for patients. This article presents the mechanism of dPDT, indications for this method as well as its efficiency, side effects, advantages and disadvantages. In the end, current treatment protocols of dPDT are presented.
目前，光动力疗法（PDT）被广泛应用，主要用于治疗光化性角化病（AK），尤其是根据奥尔森分类法的I级和II级。主要副作用包括照射期间的灼痛、刺痛和疼痛。替代方案包括日光光动力疗法（dPDT），即在涂抹光敏剂后使用阳光而非人造光。与传统光动力疗法不同，日光疗法对患者来说疼痛较轻且更舒适。本文介绍了日光光动力疗法的机制、该方法的适应症及其疗效、副作用、优缺点。最后，介绍了目前日光光动力疗法的治疗方案。
