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去甲丙咪嗪治疗抑郁症后的生长激素释放

Growth hormone release after desipramine in depressive illness.

作者信息

Meesters P, Kerkhofs M, Charles G, Decoster C, Vanderelst M, Mendlewicz J

出版信息

Eur Arch Psychiatry Neurol Sci. 1985;235(3):140-2. doi: 10.1007/BF00380983.

DOI:10.1007/BF00380983
PMID:4092710
Abstract

The effect of i.m. administration of 75 mg of desipramine on growth hormone (GH) secretion was investigated in a sample of 87 patients with major depressive disorders and in 31 normal controls. The GH response was lower in depressed females compared to depressed males, but no such difference was present in controls. In the premenopausal female group, GH response was significantly lower in depressed patients than in controls. No significant difference was found between normal males and male depressed patients. In the premenopausal group, no difference emerged between endogenous and nonendogenous depressed women.

摘要

在87例重度抑郁症患者和31例正常对照样本中,研究了肌肉注射75毫克去甲丙咪嗪对生长激素(GH)分泌的影响。与抑郁男性相比,抑郁女性的GH反应较低,但对照组中不存在这种差异。在绝经前女性组中,抑郁患者的GH反应显著低于对照组。正常男性和男性抑郁患者之间未发现显著差异。在绝经前组中,内源性和非内源性抑郁女性之间未出现差异。

相似文献

1
Growth hormone release after desipramine in depressive illness.去甲丙咪嗪治疗抑郁症后的生长激素释放
Eur Arch Psychiatry Neurol Sci. 1985;235(3):140-2. doi: 10.1007/BF00380983.
2
Responses of growth hormone to desipramine in endogenous and non-endogenous depression.内源性和非内源性抑郁症中生长激素对去甲丙咪嗪的反应。
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Stimulation of growth hormone secretion by desimipramin and chlorimipramin in man.去甲丙咪嗪和氯丙咪嗪对人体生长激素分泌的刺激作用。
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