Laakmann G, Schumacher G, Benkert O
J Clin Endocrinol Metab. 1977 May;44(5):1010-3. doi: 10.1210/jcem-44-5-1010.
In twelve healthy male subjects 75 mg desimipramin (DMI) administered intramuscularly and 100 mg DMI given orally led to a prompt rise in serum growth hormone (GH) levels. The maximum level of serum GH was observed 60 min after the i.m. and 150 min after the oral administration of DMI. Chlorimipramin (CI) administered in the same manner and in the same dosages resulted in a significant increase in GH in only six out of twelve subjects. The maximum level was observed 60 min after the i.m. and 150 min after the oral administration of DMI. There was no change in the prolactin (PRL) levels after administration of DMI and CI.
在12名健康男性受试者中，肌肉注射75毫克去甲丙咪嗪（DMI）和口服100毫克DMI会导致血清生长激素（GH）水平迅速升高。肌肉注射DMI后60分钟以及口服DMI后150分钟观察到血清GH的最高水平。以相同方式和相同剂量给予氯米帕明（CI），仅在12名受试者中的6名中导致GH显著增加。最高水平在肌肉注射DMI后60分钟以及口服DMI后150分钟观察到。给予DMI和CI后催乳素（PRL）水平没有变化。
