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掺入无花果种子提取物的3D打印临时牙科树脂的颜色表征、机械性能和抗菌活性的体外评估

In vitro evaluation of color characterization, mechanical properties, and antimicrobial activity of 3D-printed provisional dental resin incorporated with Ficus carica (Fig) seed extract.

作者信息

Jei Jeyaraj Brintha, Muthukumar Balasubramaniam

机构信息

Department of Prosthodontics and Crown & Bridge, SRM Dental College, Ramapuram Campus, SRM Institute of Science and Technology, Chennai, Tamil Nadu, India.

出版信息

J Oral Biol Craniofac Res. 2025 Nov-Dec;15(6):1400-1407. doi: 10.1016/j.jobcr.2025.08.028. Epub 2025 Aug 28.

Abstract

BACKGROUND OF THE STUDY

known for its bioactive phytochemicals and antimicrobial potential; however, studies evaluating its outcome on the color, mechanical properties and antimicrobial activity of 3D-printed provisional dental resins are lacking. So this study evaluate the effect of seed extract incorporation on the color assessment, flexural strength, compressive strength, microhardness and antimicrobial activity of 3D-printed provisional crown and bridge resin.

MATERIALS AND METHODS

A total of 240 samples were prepared, with 60 samples allocated to four groups based on 0 %, 1.5 %, 2.5 %, and 5 % of seed extract incorporated into 3D provisional resin. Color analysis was evaluated using a spectrophotometer at baseline. Mechanical properties including flexural strength, compressive strength, and Vickers microhardness were assessed according to standardized protocols. Antimicrobial activity was tested against C albicans, S aureus, and P gingivalis by measuring zones of inhibition and calculating colony-forming units (CFU/mL). Data were analyzed using one-way ANOVA, followed by Tukey's HSD post hoc test. A p-value of <0.05 was considered statistically significant.

RESULTS

Color property improved, with ΔE decreasing from 0.5042 ± 0.186 (control) to 0.0700 ± 0.026 in the 5 % group, remaining within clinically acceptable limits. The Group D (5 %) showed significantly enhanced mechanical properties compared to the control (p < 0.001). Mean compressive strength increased from 65.92 ± 1.02 MPa (control) to 76.09 ± 0.57 MPa in the 5 % group. Flexural strength improved from 55.77 ± 0.49 MPa to 69.53 ± 0.60 MPa, and microhardness increased from 11.17 ± 0.50 VHN to 14.02 ± 0.31 VHN. Antimicrobial activity demonstrated a dose-dependent increase, with the 5 % group showing the highest inhibition zones and greatest reduction in microbial counts across all tested organisms.

CONCLUSION

seed extract incorporation especially at 5 % enhances the mechanical strength, color, and antimicrobial efficacy of 3D-printed provisional crown and bridge resin.

摘要

研究背景

以其生物活性植物化学物质和抗菌潜力而闻名;然而,缺乏评估其对3D打印临时牙科树脂的颜色、机械性能和抗菌活性影响的研究。因此,本研究评估了种子提取物掺入对3D打印临时冠桥树脂的颜色评估、弯曲强度、抗压强度、显微硬度和抗菌活性的影响。

材料与方法

共制备240个样本,根据掺入3D临时树脂中的种子提取物的0%、1.5%、2.5%和5%将60个样本分为四组。在基线时使用分光光度计评估颜色分析。根据标准化方案评估包括弯曲强度、抗压强度和维氏显微硬度在内的机械性能。通过测量抑菌圈和计算菌落形成单位(CFU/mL)来测试对白色念珠菌、金黄色葡萄球菌和牙龈卟啉单胞菌的抗菌活性。使用单因素方差分析进行数据分析,随后进行Tukey's HSD事后检验。p值<0.05被认为具有统计学意义。

结果

颜色性能得到改善,ΔE从对照组的0.5042±0.186降至5%组的0.0700±0.026,仍在临床可接受范围内。与对照组相比,D组(5%)的机械性能显著增强(p<0.001)。平均抗压强度从对照组的65.92±1.02MPa增加到5%组的76.09±0.57MPa。弯曲强度从55.77±0.49MPa提高到69.

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e6b8/12414886/bb286720080d/ga1.jpg

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