Zhang Xia, Song Shuang, Sui Wenda, Sun Lu, Wang Zaowen, Chen Lulu, Bian Ailing, Zhong Yong, Zhang Shunhua
Department of Ophthalmology, Peking Union Medical College Hospital, Chinese Academy of Medical Science and Peking Union Medical College Hospital, No. 1 Shuaifuyuan Wangfujing Dongcheng District, China, 100730, Beijing.
Department of Biostatistics, Harvard T. H. Chan School of Public Health, Boston, MA, USA.
Graefes Arch Clin Exp Ophthalmol. 2025 Sep 10. doi: 10.1007/s00417-025-06951-1.
To evaluate the predictive value of the preoperative orientation and offset of angle alpha(chord alpha) and angle kappa(chord mu) for visual outcomes in patients who underwent trifocal intraocular lens (IOL) implantation.
Patient records of eyes that underwent AT LISA tri 839MP implantation were retrospectively collected and grouped according to the preoperative offset and orientations of chord alpha and chord mu. The two-dimensional location of each angle was described by the interaction of the orientation and offset. Multiple regression models and likelihood ratio tests were established to determine their predictive value for postoperative visual outcomes, National Eye Institute Visual Function Questionnaire (NEI-VFQ) and Quality of Vision Questionnaire (QoV) scores.
One hundred and two patients (184 eyes) were included. The orientation of chord alpha had a significant overall prediction to postoperative visual outcomes (p = 0.014). A superior chord alpha was an independent predictor of better postoperative uncorrected distance visual acuity (UDVA, p < 0.001) and a larger modulation transfer function (MTF) curve average height (p = 0.041). However, the offsets of chords alpha and chord mu and the orientation of chord mu did not significantly predict UDVA, uncorrected intermediate visual acuity (UIVA), uncorrected near visual acuity (UNVA), MTF, total ocular aberration (TOA), or high-order aberration (HOA).Better patient reported general vision was correlated with a nasal chord alpha (p = 0.012), whereas better near vision was correlated with a smaller kappa offset (p = 0.022) and nasal chord alpha (p = 0.019). The absence of postoperative halos was independently associated with the location of nasal chord alpha(p = 0.039), while starbursts were independently correlated with a larger chord mu offset (p = 0.007).
A superior chord alpha was an independent predictor of better postoperative visual outcomes after trifocal IOL implantation. The predictive value of either the orientation or offset of chord mu for the VA, TOA and HOA was insignificant.
Not applicable.
What is known The chord alpha (angle alpha) was found to be predominantly located in the temporal quadrant of the cornea, followed by the superior, nasal, and inferior quadrants. The chord mu (angle kappa) was more evenly distributed in the four quadrants, with 46.2% (85/184) in the temporal quadrant, followed by the inferior, superior, and nasal quadrants. What this paper adds A superior chord alpha orientation was an independent predictor of better postoperative uncorrected distance visual acuity (UDVA) and modulation transfer function average height (MTF AH). However, the interaction of orientation and offset had no predictive value. The orientation and offset of chord mu had no significant predictive value for UDVA, uncorrected intermediate visual acuity (UIVA), uncorrected near visual acuity (UNVA), MTF AH, total (TOA), or high-order aberration (HOA). The nasal chord alpha was independently correlated with better patient reported general vision, near vision and absence of halo. A smaller kappa offset was independently correlated with better performance in patient reported near vision and fewer starbursts.
评估三焦点人工晶状体(IOL)植入患者术前α角(弦α)和κ角(弦μ)的方位和偏移对视觉结果的预测价值。
回顾性收集接受AT LISA tri 839MP植入术的眼部患者记录,并根据术前弦α和弦μ的偏移和方位进行分组。每个角度的二维位置通过方位和偏移的相互作用来描述。建立多元回归模型和似然比检验,以确定它们对术后视觉结果、美国国立眼科研究所视觉功能问卷(NEI-VFQ)和视觉质量问卷(QoV)评分的预测价值。
纳入102例患者(184只眼)。弦α的方位对术后视觉结果有显著的总体预测作用(p = 0.014)。上方弦α是术后更好的未矫正远视力(UDVA,p < 0.001)和更大的调制传递函数(MTF)曲线平均高度(p = 0.041)的独立预测因素。然而,弦α和弦μ的偏移以及弦μ的方位对UDVA、未矫正中视力(UIVA)、未矫正近视力(UNVA)、MTF、总眼像差(TOA)或高阶像差(HOA)没有显著预测作用。患者报告的更好的总体视力与鼻侧弦α相关(p = 0.012),而更好的近视力与较小的κ偏移(p = 0.022)和鼻侧弦α(p = 0.019)相关。术后无眩光与鼻侧弦α的位置独立相关(p = 0.039),而星芒与更大的弦μ偏移独立相关(p = 0.007)。
上方弦α是三焦点IOL植入术后更好视觉结果的独立预测因素。弦μ的方位或偏移对视力、TOA和HOA的预测价值不显著。
不适用。
已知内容:发现弦α(α角)主要位于角膜的颞侧象限,其次是上方、鼻侧和下方象限。弦μ(κ角)在四个象限中分布更均匀,颞侧象限占46.2%(85/184),其次是下方、上方和鼻侧象限。本文新增内容:上方弦α方位是术后更好的未矫正远视力(UDVA)和调制传递函数平均高度(MTF AH)的独立预测因素。然而,方位和偏移的相互作用没有预测价值。弦μ的方位和偏移对UDVA、未矫正中视力(UIVA)、未矫正近视力(UNVA)、MTF AH、总(TOA)或高阶像差(HOA)没有显著预测价值。鼻侧弦α与患者报告的更好的总体视力、近视力和无眩光独立相关。较小的κ偏移与患者报告的更好的近视力表现和更少的星芒独立相关。