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比较 Pentacam 眼前节断层扫描仪、光学低相干反射测量仪和基于像差的光线追踪仪在白内障患者术前测量的角楔差异。

Comparison of preoperative angle kappa measurements in the eyes of cataract patients obtained from Pentacam Scheimpflug system, optical low-coherence reflectometry, and ray-tracing aberrometry.

机构信息

Eye Institute, Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong, 226001, Jiangsu, China.

出版信息

BMC Ophthalmol. 2022 Apr 2;22(1):153. doi: 10.1186/s12886-021-02116-w.

Abstract

BACKGROUND

Angle kappa plays a vital role in the implantation of multifocal intraocular lens (MIOL). Large angle kappa is related to a higher risk of postoperative photic phenomena. This study aims to compare preoperative angle kappa in the eyes of cataract patients obtained from the Pentacam Scheimpflug system (Pentacam), optical low-coherence reflectometry (Lenstar), and ray-tracing aberrometry (iTrace).

METHODS

One hundred thirteen eyes of 113 patients with cataracts were included. Each eye was examined 3 times using all devices to obtain angle kappa and pupil diameter. When considering dependent eyes for one individual, angle kappa in both right eyes and left eyes should be analysed separately. The repeatability and reproducibility were evaluated using the within-subject standard deviation (Sw), repeatability (2.77 Sw), and intraclass correlation coefficient (ICC). The difference, correlation, and agreement between devices were evaluated by paired t-tests, Pearson tests, and Bland-Altman analysis, respectively.

RESULTS

Intraoperator repeatability and interoperator and intersession reproducibility of angle kappa showed an Sw of less than 0.05 mm, a 2.77 Sw of 0.14 mm or less, and an ICC of more than 0.96. Angle kappa was not significantly different between Pentacam and Lenstar (P > 0.05), while angle kappa was significantly different between Pentacam and iTrace and between Lenstar and iTrace (P < 0.05). There was a strong correlation between Pentacam and Lenstar for angle kappa (r =0.907 to 0.918) and a weak or moderate correlation between Pentacam and iTrace and between Lenstar and iTrace (r =0.292 to 0.618). There were narrow 95% limits of agreement (LoA) between Pentacam and Lenstar for angle kappa and wide 95% LoA between Pentacam and iTrace and between Lenstar and iTrace. No significant differences in pupil diameter were found between Pentacam and Lenstar in either eye (P > 0.05). Positive angle kappa (nasal light reflex) was found in most cataract patients (79.25% to 84.91%) through 3 different devices in both eyes.

CONCLUSIONS

The 3 devices provided high intraoperator repeatability and interoperator and intersession reproducibility for angle kappa measurements. The measurement of preoperative angle kappa in the eyes of patients with cataracts by Pentacam and Lenstar has good agreement.

摘要

背景

角kappa 在多焦点人工晶状体(MIOL)的植入中起着至关重要的作用。大角度 kappa 与术后光幻现象的风险增加有关。本研究旨在比较白内障患者眼中使用 Pentacam Scheimpflug 系统(Pentacam)、光学低相干反射计(Lenstar)和光线追踪像差仪(iTrace)获得的术前角 kappa。

方法

纳入 113 例 113 只眼白内障患者。使用所有设备对每只眼进行 3 次检查,以获得角 kappa 和瞳孔直径。对于一个个体的相关眼,右眼和左眼的角 kappa 应分别进行分析。通过个体内标准差(Sw)、重复性(2.77 Sw)和组内相关系数(ICC)评估重复性和再现性。通过配对 t 检验、Pearson 检验和 Bland-Altman 分析分别评估设备之间的差异、相关性和一致性。

结果

角 kappa 的操作者内重复性、操作者间和试验间再现性的 Sw 小于 0.05mm,2.77 Sw 小于或等于 0.14mm,ICC 大于 0.96。Pentacam 和 Lenstar 之间的角 kappa 无显著差异(P>0.05),而 Pentacam 和 iTrace 之间以及 Lenstar 和 iTrace 之间的角 kappa 有显著差异(P<0.05)。Pentacam 和 Lenstar 之间的角 kappa 相关性很强(r=0.907 至 0.918),而 Pentacam 和 iTrace 之间以及 Lenstar 和 iTrace 之间的相关性较弱或中等(r=0.292 至 0.618)。Pentacam 和 Lenstar 之间的角 kappa 95%限差(LoA)较窄,而 Pentacam 和 iTrace 之间以及 Lenstar 和 iTrace 之间的 95%LoA 较宽。在每只眼的 Pentacam 和 Lenstar 中均未发现瞳孔直径有显著差异(P>0.05)。通过 3 种不同设备,在双眼白内障患者中发现了较高比例的正角 kappa(79.25%至 84.91%)。

结论

3 种设备均能提供角 kappa 测量的高操作者内重复性、操作者间和试验间再现性。Pentacam 和 Lenstar 测量白内障患者术前角 kappa 具有良好的一致性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f2b8/8976989/3a4cc98e45bf/12886_2021_2116_Fig1_HTML.jpg

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