A novel macromolecular antibiotic, SN-07. Taxonomy of producing organism, isolation, characterization and biological activities.
作者信息
Kikuchi Y, Niwano M, Yajima N, Nakamura G, Miyata N
出版信息
J Antibiot (Tokyo). 1985 Dec;38(12):1670-6. doi: 10.7164/antibiotics.38.1670.
PMID:4093331
Abstract
A novel macromolecular antibiotic SN-07 was obtained from the cultural supernatant of Actinomadura roseoviolacea var. miuraensis nov. var. The antibiotic was soluble in water, had a molecular weight of 18,000-22,000 daltons in 50 mM Tris-HCl buffer, pH 7.0, containing 2.0 M KCl as compared with authentic proteins. Its major constituents were nucleic acids. The substance had antibacterial activity against Gram-positive bacteria. It was also effective against lymphocytic leukemia P388 in vivo.
摘要
相似文献
1
A novel macromolecular antibiotic, SN-07. Taxonomy of producing organism, isolation, characterization and biological activities.
J Antibiot (Tokyo). 1985 Dec;38(12):1670-6. doi: 10.7164/antibiotics.38.1670.
2
Isolation and characterization of terpentecin, a new antitumor antibiotic.新型抗肿瘤抗生素terpentecin的分离与鉴定
J Antibiot (Tokyo). 1985 Dec;38(12):1664-9. doi: 10.7164/antibiotics.38.1664.
3
Production and biological activity of marcellomycin, an antitumor anthracycline antibiotic, and taxonomy of the producing organism.
J Antibiot (Tokyo). 1982 Sep;35(9):1174-83. doi: 10.7164/antibiotics.35.1174.
4
Rubeomycin, a new anthracycline antibiotic complex. I. Taxonomy of producing organism, isolation, characterization and biological activities of rubeomycin A, A1, B and B1.
J Antibiot (Tokyo). 1981 Aug;34(8):938-50. doi: 10.7164/antibiotics.34.938.
5
Coloradocin, an antibiotic from a new Actinoplanes. I. Taxonomy, fermentation and biological properties.
J Antibiot (Tokyo). 1987 Oct;40(10):1375-82. doi: 10.7164/antibiotics.40.1375.
6
Kedarcidin, a new chromoprotein antitumor antibiotic. I. Taxonomy of producing organism, fermentation and biological activity.可达霉素，一种新型的色蛋白抗肿瘤抗生素。I. 产生菌的分类学、发酵及生物活性
J Antibiot (Tokyo). 1991 May;44(5):472-8. doi: 10.7164/antibiotics.44.472.
7
Studies on a novel antitumor antibiotic, phenazinomycin: taxonomy, fermentation, isolation, and physicochemical and biological characteristics.新型抗肿瘤抗生素吩嗪霉素的研究：分类学、发酵、分离以及物理化学和生物学特性
J Antibiot (Tokyo). 1989 Jul;42(7):1037-42. doi: 10.7164/antibiotics.42.1037.
8
Elsamicins, new antitumor antibiotics related to chartreusin. I. Production, isolation, characterization and antitumor activity.埃尔斯米星，与黄绿青霉素有关的新型抗肿瘤抗生素。I. 生产、分离、表征及抗肿瘤活性
J Antibiot (Tokyo). 1986 Jun;39(6):784-91. doi: 10.7164/antibiotics.39.784.
9
Verucopeptin, a new antitumor antibiotic active against B16 melanoma. I. Taxonomy, production, isolation, physico-chemical properties and biological activity.疣孢菌素，一种对B16黑色素瘤有活性的新型抗肿瘤抗生素。I. 分类学、生产、分离、理化性质及生物活性。
J Antibiot (Tokyo). 1993 Jun;46(6):921-7. doi: 10.7164/antibiotics.46.921.
10
New anthracycline glycosides: 4-O-demethyl-11-deoxydoxorubicin and analogues from Streptomyces peucetius var. aureus.新型蒽环类糖苷：来自佩西链霉菌金黄色变种的4-O-去甲基-11-脱氧阿霉素及其类似物。
J Antibiot (Tokyo). 1982 Feb;35(2):176-83. doi: 10.7164/antibiotics.35.176.
Zotero 插件