温度对粪肠球菌中细胞壁抗生素的最低抑菌浓度和杀菌浓度的影响。
Temperature effects on minimum inhibitory and bactericidal concentrations of cell wall antibiotics in Streptococcus faecalis.
作者信息
Hinks E T, Daneo-Moore L, Braverman S
出版信息
Antimicrob Agents Chemother. 1977 Aug;12(2):281-3. doi: 10.1128/AAC.12.2.281.
Abstract
The minimal inhibitory and bactericidal concentrations were determined at 30 and 37 degrees C for several antibiotics affecting cell wall biosynthesis. The test organism, Streptococcus faecalis ATCC 9790, possesses a single autolytic enzyme and does not produce penicillinase. Penicillin, methicillin, and, possibly, bacitracin appeared more effective at 37 than at 30 degrees C. Vancomycin, ristocetin, and phosphonomycin appeared equally effective at both temperatures, and cycloserine appeared consistently more active at 30 than at 37 degrees C.
摘要
针对几种影响细胞壁生物合成的抗生素，在30摄氏度和37摄氏度下测定了最低抑菌浓度和杀菌浓度。测试菌株粪肠球菌ATCC 9790仅有一种自溶酶，且不产生青霉素酶。青霉素、甲氧西林以及可能的杆菌肽在37摄氏度时比在30摄氏度时更有效。万古霉素、瑞斯托菌素和磷霉素在两个温度下效果相当，而环丝氨酸在30摄氏度时始终比在37摄氏度时更具活性。
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